Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties

Freeze-dried chitosan formulations solubilized in platelet-rich plasma (PRP) are currently evaluated as injectable implants with the potential for augmenting the standard of care for tissue repair in different orthopedic conditions. The present study aimed to shorten the solidification time of such...

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Veröffentlicht in:	Polymers 2023-06, Vol.15 (13), p.2919
Hauptverfasser:	Milano, Fiona, Chevrier, Anik, De Crescenzo, Gregory, Lavertu, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable implants Biological activity Biomedical materials Blood platelets Chemical properties Chitin Chitosan Coagulation Growth factors Health aspects Injectability Laboratories Materials research Orthopedics Plasma Platelet-rich plasma Platelets Regeneration (physiology) Regenerative medicine Rheological properties Rheology Rotator cuff Solidification Solubilization Surgical implants Tendons Thrombin Tissue engineering Transplants & implants Wound healing
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