CEBP-β and PLK1 as Potential Mediators of the Breast Cancer/Obesity Crosstalk: In Vitro and In Silico Analyses

Over the last two decades, obesity has reached pandemic proportions in several countries, and expanding evidence is showing its contribution to several types of malignancies, including breast cancer (BC). The conditioned medium (CM) from mature adipocytes contains a complex of secretes that may mimi...

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Veröffentlicht in:	Nutrients 2023-06, Vol.15 (13), p.2839
Hauptverfasser:	Accattatis, Felice Maria, Caruso, Amanda, Carleo, Alfonso, Del Console, Piercarlo, Gelsomino, Luca, Bonofiglio, Daniela, Giordano, Cinzia, Barone, Ines, Andò, Sebastiano, Bianchi, Laura, Catalano, Stefania
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipocytes - metabolism Adipose Tissue - metabolism Antibodies Biomarkers Body mass index Breast cancer Breast Neoplasms - metabolism Cancer therapies CCAAT/enhancer-binding protein Cell Line, Tumor Cell Proliferation Cells Female Gene expression Humans Insulin Integrated software Kinases Lipids Malignancy MCF-7 Cells Medical prognosis Medical research Obesity Obesity - metabolism Ontology Overweight Physiology Polo-like kinase 1 Protein binding Protein kinases Proteins Transcriptomics Type 2 diabetes Womens health
Online-Zugang:	Volltext
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