Deep Vein Thrombosis Is Facilitated by Endothelial-Derived Extracellular Vesicles via the PDI-GRP94-GPIIb/IIIa Pathway in Mice

Deep vein thrombosis (DVT) is a prevalent cardiovascular condition. Endothelial-derived extracellular vesicles (EVs) may play a crucial role in platelet-dependent DVT development via platelet activation, but the mechanism is not clear yet. This research aims to understand how platelets and endotheli...

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Veröffentlicht in:	Journal of clinical medicine 2023-06, Vol.12 (13), p.4265
Hauptverfasser:	Lan, Hongtao, Tong, Zhoujie, Jiao, Yaqiong, Han, Haitao, Ma, Ying, Li, Yulin, Jia, Xu, Hu, Boang, Zhang, Wei, Zhong, Ming, Wang, Zhihao
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Blood Blood platelets Cell organelles Chemical bonds Clinical medicine Development and progression Endoplasmic reticulum Endothelium Extracellular vesicles Health aspects Heat shock proteins Integrins Plasma Protein disulfide isomerases Protein-protein interactions Proteins Signal transduction Thromboembolism Thrombosis Veins & arteries Venous thrombosis
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