Innovative Pre-Clinical Data Using Peptides to Intervene in the Evolution of Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive, relentless, and deadly disease. Little is known about its pathogenetic mechanisms; therefore, developing efficient pharmacological therapies is challenging. This work aimed to apply a therapeutic alternative using immunomodulatory peptides in a c...

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Veröffentlicht in:	International journal of molecular sciences 2023-07, Vol.24 (13), p.11049
Hauptverfasser:	Simon, Karina Smidt, Coelho, Luísa Coutinho, Veloso, Jr, Paulo Henrique de Holanda, Melo-Silva, Cesar Augusto, Morais, José Athayde Vasconcelos, Longo, João Paulo Figueiró, Figueiredo, Florencio, Viana, Leonora, Silva Pereira, Ildinete, Amado, Veronica Moreira, Mortari, Marcia Renata, Bocca, Anamelia Lorenzetti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Animal models Animals Apoptosis Bleomycin Collagen Collagen Type I Cytokines Disease Enzyme-linked immunosorbent assay Fibroblasts Fibrosis Gene expression Health aspects Idiopathic Pulmonary Fibrosis - drug therapy Idiopathic Pulmonary Fibrosis - pathology Immune response Immune system Immunomodulation Inflammation Lung - pathology Lung diseases Lungs Mice Mice, Inbred C57BL Morphology Peptides Peptides - pharmacology Peptides - therapeutic use Pulmonary fibrosis Respiratory function Respiratory system
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