3D vascularised proximal tubules-on-a-multiplexed chip model for enhanced cell phenotypes

Modelling proximal tubule physiology and pharmacology is essential to understand tubular biology and guide drug discovery. To date, multiple models have been developed; however, their relevance to human disease has yet to be evaluated. Here, we report a 3D vascularized proximal tubule-on-a-multiplex...

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Veröffentlicht in:	Lab on a chip 2023-07, Vol.23 (14), p.3226-3237
Hauptverfasser:	Carracedo, Miguel, Robinson, Sanlin, Alaei, Babak, Clausen, Maryam, Hicks, Ryan, Belfield, Graham, Althage, Magnus, Bak, Annette, Lewis, Jennifer A, Hansen, Pernille B. L, Williams, Julie M
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Closed loops Endothelial cells Endothelium Epithelium Fibrin Gelatin Gene expression Inflammatory response Multiplexing Pharmacology Physiology Three dimensional flow
Online-Zugang:	Volltext
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