Meningoencephalitis caused by concurrent infection with canine distemper virus and a unique Sarcocystis sp. in a gray fox
A deceased 9-wk-old male gray fox (Urocyon cinereoargenteus) with a history of decreased ambulation and diarrhea was submitted to the Texas A&M Veterinary Medical Diagnostic Laboratory. No significant gross findings were evident on postmortem examination. Histologically, the cerebrum and brainst...
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| Veröffentlicht in: | Journal of veterinary diagnostic investigation 2023-07, Vol.35 (4), p.444-448 |
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| creator | Neupane, Sarita Wellehan, James F. X. Childress, April L. Snook, Eric R. Porter, Brian F. |
| description | A deceased 9-wk-old male gray fox (Urocyon cinereoargenteus) with a history of decreased ambulation and diarrhea was submitted to the Texas A&M Veterinary Medical Diagnostic Laboratory. No significant gross findings were evident on postmortem examination. Histologically, the cerebrum and brainstem had mild necrotizing meningoencephalitis with protozoal schizonts and merozoites. Additionally, glial cells contained intracytoplasmic and intranuclear viral inclusion bodies. Sections of the cerebrum were positive for canine distemper virus (CDV) and negative for Sarcocystis neurona on immunohistochemistry. Bayesian analysis revealed that this Sarcocystis sp. clustered most closely with a clade of unnamed Sarcocystis sp. found in viperid snakes, with a posterior probability of 99%. CDV likely played a significant role in the expression of clinical sarcocystosis in this gray fox. |
| doi_str_mv | 10.1177/10406387231169768 |
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X.</creatorcontrib><creatorcontrib>Childress, April L.</creatorcontrib><creatorcontrib>Snook, Eric R.</creatorcontrib><creatorcontrib>Porter, Brian F.</creatorcontrib><title>Meningoencephalitis caused by concurrent infection with canine distemper virus and a unique Sarcocystis sp. in a gray fox</title><title>Journal of veterinary diagnostic investigation</title><addtitle>J Vet Diagn Invest</addtitle><description>A deceased 9-wk-old male gray fox (Urocyon cinereoargenteus) with a history of decreased ambulation and diarrhea was submitted to the Texas A&M Veterinary Medical Diagnostic Laboratory. No significant gross findings were evident on postmortem examination. Histologically, the cerebrum and brainstem had mild necrotizing meningoencephalitis with protozoal schizonts and merozoites. Additionally, glial cells contained intracytoplasmic and intranuclear viral inclusion bodies. Sections of the cerebrum were positive for canine distemper virus (CDV) and negative for Sarcocystis neurona on immunohistochemistry. Bayesian analysis revealed that this Sarcocystis sp. clustered most closely with a clade of unnamed Sarcocystis sp. found in viperid snakes, with a posterior probability of 99%. CDV likely played a significant role in the expression of clinical sarcocystosis in this gray fox.</description><subject>Animals</subject><subject>Bayes Theorem</subject><subject>Brief Reports</subject><subject>Distemper</subject><subject>Distemper Virus, Canine</subject><subject>Dog Diseases</subject><subject>Dogs</subject><subject>Foxes</subject><subject>Male</subject><subject>Meningoencephalitis - pathology</subject><subject>Meningoencephalitis - veterinary</subject><subject>Sarcocystis</subject><subject>Sarcocystosis - diagnosis</subject><subject>Sarcocystosis - pathology</subject><subject>Sarcocystosis - veterinary</subject><issn>1040-6387</issn><issn>1943-4936</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtv1DAUhS1ERR_wA9ggL9lksGPHjxVCFVCkVl20e8txrmdcZexgJ4X8ezyaUoGQWNnS-c7xvT4IvaVkQ6mUHyjhRDAlW0ap0FKoF-iMas4arpl4We9Vbw7AKTov5YGQru0kfYVOmSS8JYKfofUGYojbBNHBtLNjmEPBzi4FBtyv2KXolpwhzjhED24OKeIfYd5VpvoAD6HMsJ8g48eQl4JtHLDFSwzfF8B3Nrvk1nLILNOmRlRtm-2Kffr5Gp14OxZ483ReoPsvn-8vr5rr26_fLj9dN45xNTdOCK1FT5T2Xe98zy33UjvGlO4JDJ2ySrKWWV5BkI5q6DxwN_SeDoIN7AJ9PMZOS7-HwdVVsh3NlMPe5tUkG8zfSgw7s02PhhLGKNNdTXj_lJBT3arMZh-Kg3G0EdJSTKsIoVzpTleUHlGXUykZ_PM7lJhDZeafyqrn3Z8DPjt-d1SBzREodgvmIS051v_6T-Iv61iiPA</recordid><startdate>20230701</startdate><enddate>20230701</enddate><creator>Neupane, Sarita</creator><creator>Wellehan, James F. 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Additionally, glial cells contained intracytoplasmic and intranuclear viral inclusion bodies. Sections of the cerebrum were positive for canine distemper virus (CDV) and negative for Sarcocystis neurona on immunohistochemistry. Bayesian analysis revealed that this Sarcocystis sp. clustered most closely with a clade of unnamed Sarcocystis sp. found in viperid snakes, with a posterior probability of 99%. CDV likely played a significant role in the expression of clinical sarcocystosis in this gray fox.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>37042064</pmid><doi>10.1177/10406387231169768</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0001-5692-6134</orcidid><orcidid>https://orcid.org/0000-0003-4258-3219</orcidid><orcidid>https://orcid.org/0000-0002-4026-8701</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SAGE Complete; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Bayes Theorem Brief Reports Distemper Distemper Virus, Canine Dog Diseases Dogs Foxes Male Meningoencephalitis - pathology Meningoencephalitis - veterinary Sarcocystis Sarcocystosis - diagnosis Sarcocystosis - pathology Sarcocystosis - veterinary |
| title | Meningoencephalitis caused by concurrent infection with canine distemper virus and a unique Sarcocystis sp. in a gray fox |
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