Pharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg

Limited pharmacokinetic/pharmacodynamic data are a barrier to the scale-up of dolutegravir-based antiretroviral therapy (ART) in children. We examined the pharmacokinetics/pharmacodynamics of the adult film-coated dolutegravir 50 mg tablets in children with HIV infection weighing at least 20 kg. A p...

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Veröffentlicht in:	AIDS (London) 2023-07, Vol.37 (9), p.1409-1417
Hauptverfasser:	Martyn-Dickens, Charles, Ojewale, Oluwayemisi, Sly-Moore, Eugenia, Dompreh, Albert, Enimil, Anthony, Amissah, Aikins Kofi, Bosomtwe, Dennis, Frimpong Appiah, Augustina, Sarfo, Ama D., Opoku, Theresah, Asiedu, Priscilla, Dong, Stephen K., Kusi-Amponsah, Isaac, Maranchick, Nicole, Peloquin, Charles A., Antwi, Sampson, Kwara, Awewura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - therapeutic use Child Female Heterocyclic Compounds, 3-Ring HIV Infections - drug therapy HIV-1 Humans Male Oxazines - therapeutic use Prospective Studies Pyridones - therapeutic use Tablets - therapeutic use Viral Load
Online-Zugang:	Volltext
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