Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup

Early-life establishment of tolerance to commensal bacteria at barrier surfaces carries enduring implications for immune health but remains poorly understood. Here, we showed that tolerance in skin was controlled by microbial interaction with a specialized subset of antigen-presenting cells. More pa...

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Veröffentlicht in:Immunity (Cambridge, Mass.) Mass.), 2023-06, Vol.56 (6), p.1239-1254.e7
Hauptverfasser: Weckel, Antonin, Dhariwala, Miqdad O., Ly, Kevin, Tran, Victoria M., Ojewumi, Oluwasunmisola T., Riggs, Julianne B., Gonzalez, Jeanmarie R., Dwyer, Laura R., Okoro, Joy N., Leech, John M., Bacino, Margot S., Cho, Grace D., Merana, Geil, Anandasabapathy, Niroshana, Kumamoto, Yosuke, Scharschmidt, Tiffany C.
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Sprache:eng
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