The early risk of multiple sclerosis after optic neuritis

Serial brain MRI was performed in 53 patients with clinically isolated optic neuritis. Using clinical and imaging evidence for relapse, multiple sclerosis developed within a mean of 12 months in 19 of 34 cases (56%) with brain lesions at presentation, and in only 3 of 19 cases (16%) without (Relativ...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1988-12, Vol.51 (12), p.1569-1571
Hauptverfasser:	Miller, D H, Ormerod, I E, McDonald, W I, MacManus, D G, Kendall, B E, Kingsley, D P, Moseley, I F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Female Follow-Up Studies Humans Magnetic Resonance Imaging Male Medical sciences Middle Aged Multiple Sclerosis - diagnosis Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Optic Nerve - pathology Optic Neuritis - diagnosis
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Beschreibung
Zusammenfassung:	Serial brain MRI was performed in 53 patients with clinically isolated optic neuritis. Using clinical and imaging evidence for relapse, multiple sclerosis developed within a mean of 12 months in 19 of 34 cases (56%) with brain lesions at presentation, and in only 3 of 19 cases (16%) without (Relative Risk = 6.8, p less than 0.005).
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.51.12.1569