The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome

Degenerative changes in the substantia nigra and ventral tegmental area were investigated in 104 cases of Alzheimer's disease and 13 cases of Down's syndrome. Frequencies of tangles in three groups of patients with Alzheimer's disease were 86%, 44% and 46% (54% overall) respectively....

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1989-02, Vol.52 (2), p.193-200
Hauptverfasser:	Gibb, W R, Mountjoy, C Q, Mann, D M, Lees, A J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alzheimer Disease - pathology Biological and medical sciences Cell Count Cerebral Cortex - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Down Syndrome - pathology Female Hippocampus - pathology Humans Inclusion Bodies Male Medical sciences Melanins - analysis Middle Aged Nerve Degeneration Neurofibrils - ultrastructure Neurology Neurons - ultrastructure Substantia Nigra - pathology Tegmentum Mesencephali - pathology
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