A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow-up

One hundred and one of 146 patients presenting with isolated idiopathic optic neuritis, previously reviewed in 1978, were reassessed clinically, and retyped for HLA antigens and Factor B alleles, after a mean follow-up of 11.6 years. Fifty eight patients (57%) had developed multiple sclerosis at the...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1987-06, Vol.50 (6), p.758-765
Hauptverfasser:	Francis, D A, Compston, D A, Batchelor, J R, McDonald, W I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Child Follow-Up Studies HLA Antigens - analysis HLA-DQ Antigens - analysis HLA-DR Antigens - analysis HLA-DR2 Antigen HLA-DR3 Antigen Humans Medical sciences Middle Aged Multiple Sclerosis - complications Multiple Sclerosis - diagnosis Multiple Sclerosis - immunology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Optic Neuritis - complications Phenotype Recurrence Risk
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