Human epidermal growth factor receptor 2 expression in head and neck squamous cell carcinoma: Variation within and across primary tumor sites, and implications for antigen‐specific immunotherapy

Background The purpose of this study is to describe human epidermal growth factor 2 (HER2) overexpression in head and neck squamous cell carcinoma (HNSCC) and re‐evaluate its potential as a target for HER2‐directed immunotherapies. Methods A retrospective cohort of patients with HNSCC receiving cura...

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Veröffentlicht in:	Head & neck 2021-07, Vol.43 (7), p.1983-1994
Hauptverfasser:	Warren, Emilie A. K., Anil, Joshua, Castro, Patricia D., Kemnade, Jan, Suzuki, Masataka, Hegde, Meenakshi, Hicks, John, Yu, Wendong, Sandulache, Vlad, Sikora, Andrew G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Carcinoma, Squamous Cell - therapy Epidermal growth factor ErbB-2 protein Genomes Head & neck cancer Head and Neck Neoplasms - therapy head and neck squamous cell carcinoma human epidermal growth factor receptor 2 human papilloma virus immunotherapy oropharynx Human papillomavirus Humans Immunohistochemistry Immunotherapy Metastases Receptor, ErbB-2 Retrospective Studies Squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck - therapy Tumors
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