NF‐κB/NLRP3 inflammasome axis and risk of Parkinson's disease in Type 2 diabetes mellitus: A narrative review and new perspective

Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease (AD). Genetic predisposition and immune dysfunction are involved in the pathogenesis of PD. Notably, peripheral inflammatory disorders and neuroinflammation are associated with PD neuropa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular and molecular medicine 2023-07, Vol.27 (13), p.1775-1789
Hauptverfasser:	Alrouji, Mohammed, Al‐kuraishy, Hayder M., Al‐Gareeb, Ali I., Alexiou, Athanasios, Papadakis, Marios, Jabir, Majid S., Saad, Hebatallah M., Batiha, Gaber El‐Saber
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apoptosis Autoimmune diseases Beta cells Biomarkers Body fat Cytokines Diabetes Diabetes mellitus (non-insulin dependent) Dopamine receptors Glucose Health care Hemoglobin Hyperglycemia Inflammasomes Inflammation Inflammatory diseases Insulin resistance Kinases Movement disorders Nervous system Neurodegeneration Neurodegenerative diseases Neuropathology NF-κB protein NF‐κB NLRP3 inflammasome Oxidative stress Parkinson disease Parkinson's disease Pathogenesis Pathology Pesticides Pyrin protein Review Reviews Risk factors Signal transduction Substantia nigra Synuclein Systematic review T2DM Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!