Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy

ObjectiveTo investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).MethodsThis multicentre, observational study enrolled 72 patients with AC, including rig...

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Veröffentlicht in:Heart (British Cardiac Society) 2023-07, Vol.109 (13), p.992-999
Hauptverfasser: Ramos-Maqueda, Javier, Migueles, Jairo H, Molina-Jiménez, María, Ruiz-González, David, Cabrera-Borrego, Eva, Ruiz Salas, Amalio, Soriano-Maldonado, Alberto, Jimenez-Jaimez, Juan
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container_end_page 999
container_issue 13
container_start_page 992
container_title Heart (British Cardiac Society)
container_volume 109
creator Ramos-Maqueda, Javier
Migueles, Jairo H
Molina-Jiménez, María
Ruiz-González, David
Cabrera-Borrego, Eva
Ruiz Salas, Amalio
Soriano-Maldonado, Alberto
Jimenez-Jaimez, Juan
description ObjectiveTo investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).MethodsThis multicentre, observational study enrolled 72 patients with AC, including right, left and biventricular forms of the disease, with underlying desmosomal and non-desmosomal mutations. Lifestyle physical activity, objectively monitored with accelerometers (ie, movement sensors) and RR-NSVT, identified as >188 bpm and >18 beats from a textile Holter ECG for 30 days.ResultsSixty-three patients with AC (38±17.6 years, 57% men) were included. A total of 17 patients experienced ≥1 RR-NSVTs, and a total of 35 events were recorded. The odds of occurrence of ≥1 RR-NSVT during the recording did not increase as a function of either total physical activity (OR 0.95, 95% CI (CI95%) 0.68 to 1.30 for 60 min increase) or moderate-to-vigorous activities (OR 0.89, CI95% 0.71 to 1.08 for 5 min increase). Participants presenting RR-NSVTs during the recording (n=17) did not present greater odds of RR-NSVT in the days with more time either in total physical activity (OR 1.05, CI95% 0.84 to 1.29 for additional 60 min) or moderate-to-vigorous activities (OR 1.05, CI95% 0.97 to 1.12 for additional 5 min). Physical activity levels were neither different between the patients with and without RR-NSVTs during the recording period nor in the days of occurrence of RR-NSVT compared with the rest of the days. Finally, 4 of the 35 RR-NSVTs recorded in the 30 days occurred during physical activity (3 during moderate-to-vigorous intensity and 1 during light-intensity activities).ConclusionsThese findings suggest that lifestyle physical activity is not associated with RR-NSVTs in patients with AC.
doi_str_mv 10.1136/heartjnl-2022-321824
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Lifestyle physical activity, objectively monitored with accelerometers (ie, movement sensors) and RR-NSVT, identified as &gt;188 bpm and &gt;18 beats from a textile Holter ECG for 30 days.ResultsSixty-three patients with AC (38±17.6 years, 57% men) were included. A total of 17 patients experienced ≥1 RR-NSVTs, and a total of 35 events were recorded. The odds of occurrence of ≥1 RR-NSVT during the recording did not increase as a function of either total physical activity (OR 0.95, 95% CI (CI95%) 0.68 to 1.30 for 60 min increase) or moderate-to-vigorous activities (OR 0.89, CI95% 0.71 to 1.08 for 5 min increase). Participants presenting RR-NSVTs during the recording (n=17) did not present greater odds of RR-NSVT in the days with more time either in total physical activity (OR 1.05, CI95% 0.84 to 1.29 for additional 60 min) or moderate-to-vigorous activities (OR 1.05, CI95% 0.97 to 1.12 for additional 5 min). Physical activity levels were neither different between the patients with and without RR-NSVTs during the recording period nor in the days of occurrence of RR-NSVT compared with the rest of the days. Finally, 4 of the 35 RR-NSVTs recorded in the 30 days occurred during physical activity (3 during moderate-to-vigorous intensity and 1 during light-intensity activities).ConclusionsThese findings suggest that lifestyle physical activity is not associated with RR-NSVTs in patients with AC.</description><identifier>ISSN: 1355-6037</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/heartjnl-2022-321824</identifier><identifier>PMID: 36849235</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><subject>Accelerometers ; Arrhythmias and Sudden Death ; arrhythmias, cardiac ; Cardiac arrhythmia ; Cardiomyopathies - complications ; Cardiomyopathy ; Contraindications ; Data collection ; Ejection fraction ; Electrocardiography, Ambulatory ; Exercise ; Female ; Humans ; Lifestyles ; Male ; Open source software ; Patients ; Physical fitness ; Public domain ; tachycardia, ventricular ; Tachycardia, Ventricular - complications ; Tachycardia, Ventricular - etiology</subject><ispartof>Heart (British Cardiac Society), 2023-07, Vol.109 (13), p.992-999</ispartof><rights>Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2023 Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b506t-f3e3572798d10ad7e057a74874438ae100a7cdc479747864b107596bc88aab163</citedby><cites>FETCH-LOGICAL-b506t-f3e3572798d10ad7e057a74874438ae100a7cdc479747864b107596bc88aab163</cites><orcidid>0000-0003-0366-6935 ; 0000-0002-4626-420X ; 0000-0001-5541-898X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314039/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314039/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36849235$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ramos-Maqueda, Javier</creatorcontrib><creatorcontrib>Migueles, Jairo H</creatorcontrib><creatorcontrib>Molina-Jiménez, María</creatorcontrib><creatorcontrib>Ruiz-González, David</creatorcontrib><creatorcontrib>Cabrera-Borrego, Eva</creatorcontrib><creatorcontrib>Ruiz Salas, Amalio</creatorcontrib><creatorcontrib>Soriano-Maldonado, Alberto</creatorcontrib><creatorcontrib>Jimenez-Jaimez, Juan</creatorcontrib><title>Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy</title><title>Heart (British Cardiac Society)</title><addtitle>Heart</addtitle><addtitle>Heart</addtitle><description>ObjectiveTo investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).MethodsThis multicentre, observational study enrolled 72 patients with AC, including right, left and biventricular forms of the disease, with underlying desmosomal and non-desmosomal mutations. Lifestyle physical activity, objectively monitored with accelerometers (ie, movement sensors) and RR-NSVT, identified as &gt;188 bpm and &gt;18 beats from a textile Holter ECG for 30 days.ResultsSixty-three patients with AC (38±17.6 years, 57% men) were included. A total of 17 patients experienced ≥1 RR-NSVTs, and a total of 35 events were recorded. The odds of occurrence of ≥1 RR-NSVT during the recording did not increase as a function of either total physical activity (OR 0.95, 95% CI (CI95%) 0.68 to 1.30 for 60 min increase) or moderate-to-vigorous activities (OR 0.89, CI95% 0.71 to 1.08 for 5 min increase). Participants presenting RR-NSVTs during the recording (n=17) did not present greater odds of RR-NSVT in the days with more time either in total physical activity (OR 1.05, CI95% 0.84 to 1.29 for additional 60 min) or moderate-to-vigorous activities (OR 1.05, CI95% 0.97 to 1.12 for additional 5 min). Physical activity levels were neither different between the patients with and without RR-NSVTs during the recording period nor in the days of occurrence of RR-NSVT compared with the rest of the days. Finally, 4 of the 35 RR-NSVTs recorded in the 30 days occurred during physical activity (3 during moderate-to-vigorous intensity and 1 during light-intensity activities).ConclusionsThese findings suggest that lifestyle physical activity is not associated with RR-NSVTs in patients with AC.</description><subject>Accelerometers</subject><subject>Arrhythmias and Sudden Death</subject><subject>arrhythmias, cardiac</subject><subject>Cardiac arrhythmia</subject><subject>Cardiomyopathies - complications</subject><subject>Cardiomyopathy</subject><subject>Contraindications</subject><subject>Data collection</subject><subject>Ejection fraction</subject><subject>Electrocardiography, Ambulatory</subject><subject>Exercise</subject><subject>Female</subject><subject>Humans</subject><subject>Lifestyles</subject><subject>Male</subject><subject>Open source software</subject><subject>Patients</subject><subject>Physical fitness</subject><subject>Public domain</subject><subject>tachycardia, ventricular</subject><subject>Tachycardia, Ventricular - complications</subject><subject>Tachycardia, Ventricular - etiology</subject><issn>1355-6037</issn><issn>1468-201X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kUuLFDEURgtRnHH0H4gE3LgpzTuplcjgCxrcKLgLt1LpqTRVSU-Saqh_P-npmfEBukrIPTm5N1_TvCT4LSFMvhsdpLILU0sxpS2jRFP-qDknXOp6RH4-rnsmRCsxU2fNs5x3GGPeafm0OWNS844ycd5cb_zW5bJODu3HNXsLEwJb_MGXFUEYUIK9H9oExaEQQ5uXXMAHN6CDCyV5u0yQUAE7rhbS4AH5gCClcS3jHK9c8BbdFuK8xj2UcX3ePNnClN2Lu_Wi-fHp4_fLL-3m2-evlx82bS-wLO2WOSYUVZ0eCIZBOSwUKK4V50yDIxiDsoPlqlNcacl7gpXoZG-1BuiJZBfN-5N3v_SzG-yxXZjMPvkZ0moiePNnJfjRXMWDIZgRjllXDW_uDCleL_WXzOyzddMEwcUlG6o0VlIILSr6-i90F5cU6nyGaiqk4OpW-G-quogiHSOV4ifKpphzctuHngk2x-jNffTmGL05RV-vvfp93odL91lXAJ-Aft79evi_zhvh9b3w</recordid><startdate>20230701</startdate><enddate>20230701</enddate><creator>Ramos-Maqueda, Javier</creator><creator>Migueles, Jairo H</creator><creator>Molina-Jiménez, María</creator><creator>Ruiz-González, David</creator><creator>Cabrera-Borrego, Eva</creator><creator>Ruiz Salas, Amalio</creator><creator>Soriano-Maldonado, Alberto</creator><creator>Jimenez-Jaimez, Juan</creator><general>BMJ Publishing Group Ltd and British Cardiovascular Society</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0366-6935</orcidid><orcidid>https://orcid.org/0000-0002-4626-420X</orcidid><orcidid>https://orcid.org/0000-0001-5541-898X</orcidid></search><sort><creationdate>20230701</creationdate><title>Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy</title><author>Ramos-Maqueda, Javier ; Migueles, Jairo H ; Molina-Jiménez, María ; Ruiz-González, David ; Cabrera-Borrego, Eva ; Ruiz Salas, Amalio ; Soriano-Maldonado, Alberto ; Jimenez-Jaimez, Juan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b506t-f3e3572798d10ad7e057a74874438ae100a7cdc479747864b107596bc88aab163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Accelerometers</topic><topic>Arrhythmias and Sudden Death</topic><topic>arrhythmias, cardiac</topic><topic>Cardiac arrhythmia</topic><topic>Cardiomyopathies - complications</topic><topic>Cardiomyopathy</topic><topic>Contraindications</topic><topic>Data collection</topic><topic>Ejection fraction</topic><topic>Electrocardiography, Ambulatory</topic><topic>Exercise</topic><topic>Female</topic><topic>Humans</topic><topic>Lifestyles</topic><topic>Male</topic><topic>Open source software</topic><topic>Patients</topic><topic>Physical fitness</topic><topic>Public domain</topic><topic>tachycardia, ventricular</topic><topic>Tachycardia, Ventricular - complications</topic><topic>Tachycardia, Ventricular - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ramos-Maqueda, Javier</creatorcontrib><creatorcontrib>Migueles, Jairo H</creatorcontrib><creatorcontrib>Molina-Jiménez, María</creatorcontrib><creatorcontrib>Ruiz-González, David</creatorcontrib><creatorcontrib>Cabrera-Borrego, Eva</creatorcontrib><creatorcontrib>Ruiz Salas, Amalio</creatorcontrib><creatorcontrib>Soriano-Maldonado, Alberto</creatorcontrib><creatorcontrib>Jimenez-Jaimez, Juan</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Heart (British Cardiac Society)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ramos-Maqueda, Javier</au><au>Migueles, Jairo H</au><au>Molina-Jiménez, María</au><au>Ruiz-González, David</au><au>Cabrera-Borrego, Eva</au><au>Ruiz Salas, Amalio</au><au>Soriano-Maldonado, Alberto</au><au>Jimenez-Jaimez, Juan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy</atitle><jtitle>Heart (British Cardiac Society)</jtitle><stitle>Heart</stitle><addtitle>Heart</addtitle><date>2023-07-01</date><risdate>2023</risdate><volume>109</volume><issue>13</issue><spage>992</spage><epage>999</epage><pages>992-999</pages><issn>1355-6037</issn><eissn>1468-201X</eissn><abstract>ObjectiveTo investigate the association of accelerometer-measured lifestyle physical activity with rapid-rate non-sustained ventricular tachycardias (RR-NSVTs) in patients with arrhythmogenic cardiomyopathy (AC).MethodsThis multicentre, observational study enrolled 72 patients with AC, including right, left and biventricular forms of the disease, with underlying desmosomal and non-desmosomal mutations. Lifestyle physical activity, objectively monitored with accelerometers (ie, movement sensors) and RR-NSVT, identified as &gt;188 bpm and &gt;18 beats from a textile Holter ECG for 30 days.ResultsSixty-three patients with AC (38±17.6 years, 57% men) were included. A total of 17 patients experienced ≥1 RR-NSVTs, and a total of 35 events were recorded. The odds of occurrence of ≥1 RR-NSVT during the recording did not increase as a function of either total physical activity (OR 0.95, 95% CI (CI95%) 0.68 to 1.30 for 60 min increase) or moderate-to-vigorous activities (OR 0.89, CI95% 0.71 to 1.08 for 5 min increase). Participants presenting RR-NSVTs during the recording (n=17) did not present greater odds of RR-NSVT in the days with more time either in total physical activity (OR 1.05, CI95% 0.84 to 1.29 for additional 60 min) or moderate-to-vigorous activities (OR 1.05, CI95% 0.97 to 1.12 for additional 5 min). Physical activity levels were neither different between the patients with and without RR-NSVTs during the recording period nor in the days of occurrence of RR-NSVT compared with the rest of the days. Finally, 4 of the 35 RR-NSVTs recorded in the 30 days occurred during physical activity (3 during moderate-to-vigorous intensity and 1 during light-intensity activities).ConclusionsThese findings suggest that lifestyle physical activity is not associated with RR-NSVTs in patients with AC.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Cardiovascular Society</pub><pmid>36849235</pmid><doi>10.1136/heartjnl-2022-321824</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0366-6935</orcidid><orcidid>https://orcid.org/0000-0002-4626-420X</orcidid><orcidid>https://orcid.org/0000-0001-5541-898X</orcidid><oa>free_for_read</oa></addata></record>
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subjects Accelerometers
Arrhythmias and Sudden Death
arrhythmias, cardiac
Cardiac arrhythmia
Cardiomyopathies - complications
Cardiomyopathy
Contraindications
Data collection
Ejection fraction
Electrocardiography, Ambulatory
Exercise
Female
Humans
Lifestyles
Male
Open source software
Patients
Physical fitness
Public domain
tachycardia, ventricular
Tachycardia, Ventricular - complications
Tachycardia, Ventricular - etiology
title Lifestyle physical activity and rapid-rate non-sustained ventricular tachycardia in arrhythmogenic cardiomyopathy
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