Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data

Tumor heterogeneity is a complex and widely recognized trait that poses significant challenges in developing effective cancer therapies. In particular, many tumors harbor a variety of subpopulations with distinct therapeutic response characteristics. Characterizing this heterogeneity by determining...

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Veröffentlicht in:	ArXiv.org 2023-06
Hauptverfasser:	Wu, C, Gunnarsson, E B, Myklebust, E M, Köhn-Luque, A, Tadele, D S, Enserink, J M, Frigessi, A, Foo, J, Leder, K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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