Porcine Deltacoronavirus Infection Disrupts the Intestinal Mucosal Barrier and Inhibits Intestinal Stem Cell Differentiation to Goblet Cells via the Notch Signaling Pathway

Goblet cells and their secreted mucus are important elements of the intestinal mucosal barrier, which allows host cells to resist invasion by intestinal pathogens. Porcine deltacoronavirus (PDCoV) is an emerging swine enteric virus that causes severe diarrhea in pigs and causes large economic losses...

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Veröffentlicht in:Journal of virology 2023-06, Vol.97 (6), p.e0068923-e0068923
Hauptverfasser: Zhang, Shuai, Zhang, Shuoshuo, Hou, Yuchen, Huang, Yanjie, Cai, Jiajia, Wang, Guangzheng, Cao, Yanan, Chen, Zhenhai, Fang, Xiaomin, Bao, Wenbin
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Sprache:eng
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