PANX2 and brain lower grade glioma genesis: A bioinformatic analysis

PANX2 forms large-pore channels mediating ATP release in response to physiological and pathological stimuli. Although PANX2 shows involvements in glioma genesis, the underlying mechanism remains unclear. PANX2 mRNA expression was analyzed via Oncomine and was confirmed via Gene Expression Profiling...

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Veröffentlicht in:	Science progress (1916) 2021-04, Vol.104 (2), p.1-20
Hauptverfasser:	Xu, XiaoXue, Hao, YueHan, Xiong, Shuang, He, ZhiYi
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Brain - metabolism Brain - pathology Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - pathology Calcium signalling CD4 antigen Computational Biology Connexins - genetics Connexins - metabolism Dendritic cells Encyclopedias Evaluation Gene expression Genes Genomes Glioma Glioma - genetics Glioma - metabolism Glioma - pathology Humans Ligands Lymphocytes Lymphocytes T Macrophages Medical prognosis Pathogenesis Protein interaction Proteins Receptors Regression analysis Synaptic transmission Therapeutic targets
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