Intrathecal CD8 + CD20 + T Cells in Primary Progressive Multiple Sclerosis

Despite accumulating evidence of intrathecal inflammation in patients with primary progressive multiple sclerosis (PPMS), immunomodulatory and suppressive treatment strategies have proven unsuccessful. With this study, we investigated the involvement of CD20 T cells and the effect of dimethyl fumara...

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Veröffentlicht in:	Neurology : neuroimmunology & neuroinflammation 2023-09, Vol.10 (5)
Hauptverfasser:	von Essen, Marina Rode, Talbot, Jacob, Hansen, Rikke Holm Holm, Chow, Helene Højsgaard, Lundell, Henrik, Siebner, Hartwig Roman, Sellebjerg, Finn
Format:	Artikel
Sprache:	eng
Schlagworte:	Case-Control Studies CD8-Positive T-Lymphocytes Dimethyl Fumarate - pharmacology Dimethyl Fumarate - therapeutic use Humans Multiple Sclerosis - pathology Multiple Sclerosis, Chronic Progressive - drug therapy Multiple Sclerosis, Chronic Progressive - pathology Myelin Basic Protein T-Lymphocytes
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