LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice

Chaperone-mediated autophagy (CMA) selectively degrades proteins that are crucial for glycolysis, fatty acid metabolism, and the progression of several age-associated diseases. Several previous studies, each of which evaluated males of a single inbred mouse or rat strain, have reported that CMA decl...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2023-06, Vol.15 (11), p.4685-4698
Hauptverfasser:	Zhang, Katherine K, Zhang, Peichuan, Kodur, Anagha, Erturk, Ilkim, Burns, Calvin M, Kenyon, Cynthia, Miller, Richard A, Endicott, S Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Animals Autophagy - genetics Autophagy-Related Proteins - metabolism Chaperone-Mediated Autophagy - genetics Female Lysosomal-Associated Membrane Protein 2 - metabolism Lysosomes - metabolism Male Mice Molecular Chaperones - genetics Molecular Chaperones - metabolism Rats Research Paper
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