Myasthenia Gravis Associated With COVID-19 Infection
COVID-19 first emerged in Wuhan, China in late December 2019. The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthe...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-05, Vol.15 (5), p.e39506 |
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| creator | Sadiq, Waleed Waleed, Madeeha Subhan Rizvi, Taqi A Khan, Shahkar El Hage, Halim |
| description | COVID-19 first emerged in Wuhan, China in late December 2019. The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthenia gravis (MG). We discuss the cases of COVID-19 and MG already described in the literature in regard to their presentation and serological findings to better understand the association between the two disease processes. MG may be missed in patients after COVID-19 infections because of the comorbidities and anti-acetylcholine receptor and anti-muscle-specific tyrosine kinase antibodies being negative. Evidence from more studies will help analyze the pathological timeline of the disease process and the immunological characteristics of COVID-19-induced MG which can prove to have morbidity and mortality benefit in patients with COVID-19-induced MG. |
| doi_str_mv | 10.7759/cureus.39506 |
| format | Article |
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The disease majorly involves the lungs leading to various respiratory complications; however, neurological manifestations of the disease are also described in the literature. Here, we report a case of COVID-19-induced seronegative myasthenia gravis (MG). We discuss the cases of COVID-19 and MG already described in the literature in regard to their presentation and serological findings to better understand the association between the two disease processes. MG may be missed in patients after COVID-19 infections because of the comorbidities and anti-acetylcholine receptor and anti-muscle-specific tyrosine kinase antibodies being negative. Evidence from more studies will help analyze the pathological timeline of the disease process and the immunological characteristics of COVID-19-induced MG which can prove to have morbidity and mortality benefit in patients with COVID-19-induced MG.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.39506</identifier><identifier>PMID: 37366447</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Antibodies ; Apheresis ; Autoimmune diseases ; Blood ; Case reports ; Comorbidity ; COVID-19 ; COVID-19 diagnostic tests ; Disease ; Emergency medical care ; Guillain-Barre syndrome ; Immunoglobulins ; Infections ; Infectious Disease ; Internal Medicine ; Kinases ; Laboratories ; Lipoproteins ; Myasthenia gravis ; Patients ; Proteins ; Pulmonology ; Ventilators</subject><ispartof>Curēus (Palo Alto, CA), 2023-05, Vol.15 (5), p.e39506</ispartof><rights>Copyright © 2023, Sadiq et al.</rights><rights>Copyright © 2023, Sadiq et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Sadiq et al. 2023 Sadiq et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c267t-2977162b4395d88d800ab2fbd60783bb7ad0b4977a36cae1b51dfedf6e56cad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290576/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290576/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37366447$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sadiq, Waleed</creatorcontrib><creatorcontrib>Waleed, Madeeha Subhan</creatorcontrib><creatorcontrib>Rizvi, Taqi A</creatorcontrib><creatorcontrib>Khan, Shahkar</creatorcontrib><creatorcontrib>El Hage, Halim</creatorcontrib><title>Myasthenia Gravis Associated With COVID-19 Infection</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>COVID-19 first emerged in Wuhan, China in late December 2019. 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| subjects | Antibodies Apheresis Autoimmune diseases Blood Case reports Comorbidity COVID-19 COVID-19 diagnostic tests Disease Emergency medical care Guillain-Barre syndrome Immunoglobulins Infections Infectious Disease Internal Medicine Kinases Laboratories Lipoproteins Myasthenia gravis Patients Proteins Pulmonology Ventilators |
| title | Myasthenia Gravis Associated With COVID-19 Infection |
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