Modulation of dopamine release by ethanol is mediated by atypical GABAA receptors on cholinergic interneurons in the nucleus accumbens

Previous studies indicate that moderate‐to‐high ethanol (EtOH) concentrations enhance dopamine (DA) neurotransmission in the mesolimbic DA system from the ventral tegmental area (VTA) and projecting to the nucleus accumbens core (NAc). However, voltammetry studies demonstrate that moderate‐to‐high E...

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Veröffentlicht in:	Addiction biology 2022-01, Vol.27 (1), p.e13108-n/a
Hauptverfasser:	Yorgason, Jordan T., Wadsworth, Hillary A., Anderson, Elizabeth J., Williams, Benjamin M., Brundage, James N., Hedges, David M., Stockard, Alyssa L., Jones, Stephen T., Arthur, Summer B., Hansen, David Micah, Schilaty, Nathan D., Jang, Eun Young, Lee, Anna M., Wallner, Martin, Steffensen, Scott C.
Format:	Artikel
Sprache:	eng
Schlagworte:	accumbens alcohol Antagonists cholinergic Dopamine Electrophysiology Ethanol Firing rate GABA Genetics Immunohistochemistry Information processing Interneurons Mesolimbic system Neurotransmission nicotinic Nucleus accumbens Optics Strychnine Transgenic mice Ventral tegmentum Voltammetry γ-Aminobutyric acid A receptors
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