A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial
To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss. Participants were randomised into two groups: (i)...
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| Veröffentlicht in: | Public health nutrition 2014-03, Vol.17 (3), p.640-647 |
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| creator | Stuart, Keren Louise Wyld, Belinda Bastiaans, Kathryn Stocks, Nigel Brinkworth, Grant Mohr, Phil Noakes, Manny |
| description | To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss.
Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.
Two general practices in Adelaide, South Australia.
Forty-nine men and women aged 48·0 (sd 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (sd 5·39) kg/m2; LDL cholesterol (LDL-C) = 2·66 (sd 0·92) mmol/l).
CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (EM) = 1·98 (se 0·17) mmol/l) and total cholesterol (EM = 3·61 (se 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (se 0·18) mmol/l and EM = 4·77 (se 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (F(1,45) = 0·28, P = 0·60), diastolic blood pressure (F(1,43) = 0·52, P = 0·47), weight (F(1,42) = 3·63, P = 0·063) or waist circumference (F(1,43) = 0·32, P = 0·577).
In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted. |
| doi_str_mv | 10.1017/S1368980013000220 |
| format | Article |
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Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.
Two general practices in Adelaide, South Australia.
Forty-nine men and women aged 48·0 (sd 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (sd 5·39) kg/m2; LDL cholesterol (LDL-C) = 2·66 (sd 0·92) mmol/l).
CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (EM) = 1·98 (se 0·17) mmol/l) and total cholesterol (EM = 3·61 (se 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (se 0·18) mmol/l and EM = 4·77 (se 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (F(1,45) = 0·28, P = 0·60), diastolic blood pressure (F(1,43) = 0·52, P = 0·47), weight (F(1,42) = 3·63, P = 0·063) or waist circumference (F(1,43) = 0·32, P = 0·577).
In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted.</description><identifier>ISSN: 1368-9800</identifier><identifier>EISSN: 1475-2727</identifier><identifier>DOI: 10.1017/S1368980013000220</identifier><identifier>PMID: 23452940</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Air. Soil. Water. Waste. Feeding ; Biological and medical sciences ; Blood pressure ; Body Mass Index ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - prevention & control ; Cholesterol ; Cholesterol, LDL - blood ; Coaching ; Counseling ; Counseling - methods ; Environment. Living conditions ; Exercise ; Feeding Behavior - psychology ; Female ; General Practice - methods ; Humans ; Hyperlipidemia ; Hypertension - diagnosis ; Hypertension - therapy ; Intervention ; Interventions ; Life Style ; Lifestyles ; Lipids ; Male ; Medical sciences ; Middle Aged ; Overweight ; Patient Education as Topic ; Patients ; Pilot Projects ; Prevention ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Referral and Consultation ; Risk Reduction Behavior ; Self report ; Social Support ; South Australia ; Telemedicine - methods ; Telephone ; Treatment Outcome ; Weight control ; Weight Loss</subject><ispartof>Public health nutrition, 2014-03, Vol.17 (3), p.640-647</ispartof><rights>Copyright © The Authors 2013</rights><rights>2015 INIST-CNRS</rights><rights>The Authors 2013 2013 The Authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c535t-a4dfbb2aa6f2bccaef8e140ba2b91b430ee0c6e5f0b48aea3e309688c9c28fd23</citedby><cites>FETCH-LOGICAL-c535t-a4dfbb2aa6f2bccaef8e140ba2b91b430ee0c6e5f0b48aea3e309688c9c28fd23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282359/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282359/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28188799$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23452940$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stuart, Keren Louise</creatorcontrib><creatorcontrib>Wyld, Belinda</creatorcontrib><creatorcontrib>Bastiaans, Kathryn</creatorcontrib><creatorcontrib>Stocks, Nigel</creatorcontrib><creatorcontrib>Brinkworth, Grant</creatorcontrib><creatorcontrib>Mohr, Phil</creatorcontrib><creatorcontrib>Noakes, Manny</creatorcontrib><title>A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial</title><title>Public health nutrition</title><addtitle>Public Health Nutr</addtitle><description>To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss.
Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.
Two general practices in Adelaide, South Australia.
Forty-nine men and women aged 48·0 (sd 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (sd 5·39) kg/m2; LDL cholesterol (LDL-C) = 2·66 (sd 0·92) mmol/l).
CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (EM) = 1·98 (se 0·17) mmol/l) and total cholesterol (EM = 3·61 (se 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (se 0·18) mmol/l and EM = 4·77 (se 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (F(1,45) = 0·28, P = 0·60), diastolic blood pressure (F(1,43) = 0·52, P = 0·47), weight (F(1,42) = 3·63, P = 0·063) or waist circumference (F(1,43) = 0·32, P = 0·577).
In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted.</description><subject>Adult</subject><subject>Air. Soil. Water. Waste. Feeding</subject><subject>Biological and medical sciences</subject><subject>Blood pressure</subject><subject>Body Mass Index</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Cholesterol</subject><subject>Cholesterol, LDL - blood</subject><subject>Coaching</subject><subject>Counseling</subject><subject>Counseling - methods</subject><subject>Environment. Living conditions</subject><subject>Exercise</subject><subject>Feeding Behavior - psychology</subject><subject>Female</subject><subject>General Practice - methods</subject><subject>Humans</subject><subject>Hyperlipidemia</subject><subject>Hypertension - diagnosis</subject><subject>Hypertension - therapy</subject><subject>Intervention</subject><subject>Interventions</subject><subject>Life Style</subject><subject>Lifestyles</subject><subject>Lipids</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Overweight</subject><subject>Patient Education as Topic</subject><subject>Patients</subject><subject>Pilot Projects</subject><subject>Prevention</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Referral and Consultation</subject><subject>Risk Reduction Behavior</subject><subject>Self report</subject><subject>Social Support</subject><subject>South Australia</subject><subject>Telemedicine - methods</subject><subject>Telephone</subject><subject>Treatment Outcome</subject><subject>Weight control</subject><subject>Weight Loss</subject><issn>1368-9800</issn><issn>1475-2727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqNkl2L1TAQhoso7rr6A7yRgAjrRTUfzUnqjSwHPxYOKKjXZZpOe7KkTU3Slf1B_k9T9riuiuBVBuaZd96ZTFE8ZvQFo0y9_MTERteaUiYopZzTO8Uxq5QsueLqbo5zulzzR8WDGC8yI5VS94sjLirJ64oeF9_PSEKH895PWMZlnn1I2BEDobP-EqJZHATibI8xXTkkc_BDgHFEcrrdnX98Tnq_pmfbkYDdYpL1E4GpI9_QDvtEnI-R2IkMOGEAl-shMyYLQbI4pfiKAAm5wI82ro39lIJ3LoezdT6RFCy4h8W9HlzER4f3pPjy9s3n7fty9-Hd-fZsVxopZCqh6vq25QCbnrfGAPYaWUVb4G3N2kpQRGo2KHvaVhoQBApab7Q2teG677g4KV5f685LO2JnssFsupmDHSFcNR5s83tmsvtm8JcNo1xzIeuscHpQCP7rkpfW5LkMOgcT-iU2TLKNkpIp_R8orSsmtJQZffoHeuGXMOVVrJRSstayyhS7pkzIWw_Y3xhntFkPpvnrYHLNk9sT31T8vJAMPDsA-RjA9fmvjI2_OM20VvU6uDg0h7ENthvwlsd_tv8B1FjcJA</recordid><startdate>20140301</startdate><enddate>20140301</enddate><creator>Stuart, Keren Louise</creator><creator>Wyld, Belinda</creator><creator>Bastiaans, Kathryn</creator><creator>Stocks, Nigel</creator><creator>Brinkworth, Grant</creator><creator>Mohr, Phil</creator><creator>Noakes, Manny</creator><general>Cambridge University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RQ</scope><scope>7RV</scope><scope>7T2</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QO</scope><scope>7U1</scope><scope>7U2</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>20140301</creationdate><title>A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial</title><author>Stuart, Keren Louise ; Wyld, Belinda ; Bastiaans, Kathryn ; Stocks, Nigel ; Brinkworth, Grant ; Mohr, Phil ; Noakes, Manny</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c535t-a4dfbb2aa6f2bccaef8e140ba2b91b430ee0c6e5f0b48aea3e309688c9c28fd23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Air. Soil. Water. Waste. Feeding</topic><topic>Biological and medical sciences</topic><topic>Blood pressure</topic><topic>Body Mass Index</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Cholesterol</topic><topic>Cholesterol, LDL - blood</topic><topic>Coaching</topic><topic>Counseling</topic><topic>Counseling - methods</topic><topic>Environment. Living conditions</topic><topic>Exercise</topic><topic>Feeding Behavior - psychology</topic><topic>Female</topic><topic>General Practice - methods</topic><topic>Humans</topic><topic>Hyperlipidemia</topic><topic>Hypertension - diagnosis</topic><topic>Hypertension - therapy</topic><topic>Intervention</topic><topic>Interventions</topic><topic>Life Style</topic><topic>Lifestyles</topic><topic>Lipids</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Overweight</topic><topic>Patient Education as Topic</topic><topic>Patients</topic><topic>Pilot Projects</topic><topic>Prevention</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Referral and Consultation</topic><topic>Risk Reduction Behavior</topic><topic>Self report</topic><topic>Social Support</topic><topic>South Australia</topic><topic>Telemedicine - methods</topic><topic>Telephone</topic><topic>Treatment Outcome</topic><topic>Weight control</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stuart, Keren Louise</creatorcontrib><creatorcontrib>Wyld, Belinda</creatorcontrib><creatorcontrib>Bastiaans, Kathryn</creatorcontrib><creatorcontrib>Stocks, Nigel</creatorcontrib><creatorcontrib>Brinkworth, Grant</creatorcontrib><creatorcontrib>Mohr, Phil</creatorcontrib><creatorcontrib>Noakes, Manny</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Career & Technical Education Database</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Public health nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stuart, Keren Louise</au><au>Wyld, Belinda</au><au>Bastiaans, Kathryn</au><au>Stocks, Nigel</au><au>Brinkworth, Grant</au><au>Mohr, Phil</au><au>Noakes, Manny</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial</atitle><jtitle>Public health nutrition</jtitle><addtitle>Public Health Nutr</addtitle><date>2014-03-01</date><risdate>2014</risdate><volume>17</volume><issue>3</issue><spage>640</spage><epage>647</epage><pages>640-647</pages><issn>1368-9800</issn><eissn>1475-2727</eissn><abstract>To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss.
Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.
Two general practices in Adelaide, South Australia.
Forty-nine men and women aged 48·0 (sd 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (sd 5·39) kg/m2; LDL cholesterol (LDL-C) = 2·66 (sd 0·92) mmol/l).
CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (EM) = 1·98 (se 0·17) mmol/l) and total cholesterol (EM = 3·61 (se 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (se 0·18) mmol/l and EM = 4·77 (se 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (F(1,45) = 0·28, P = 0·60), diastolic blood pressure (F(1,43) = 0·52, P = 0·47), weight (F(1,42) = 3·63, P = 0·063) or waist circumference (F(1,43) = 0·32, P = 0·577).
In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>23452940</pmid><doi>10.1017/S1368980013000220</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1368-9800 |
| ispartof | Public health nutrition, 2014-03, Vol.17 (3), p.640-647 |
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| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10282359 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Air. Soil. Water. Waste. Feeding Biological and medical sciences Blood pressure Body Mass Index Cardiovascular Diseases - blood Cardiovascular Diseases - prevention & control Cholesterol Cholesterol, LDL - blood Coaching Counseling Counseling - methods Environment. Living conditions Exercise Feeding Behavior - psychology Female General Practice - methods Humans Hyperlipidemia Hypertension - diagnosis Hypertension - therapy Intervention Interventions Life Style Lifestyles Lipids Male Medical sciences Middle Aged Overweight Patient Education as Topic Patients Pilot Projects Prevention Public health. Hygiene Public health. Hygiene-occupational medicine Referral and Consultation Risk Reduction Behavior Self report Social Support South Australia Telemedicine - methods Telephone Treatment Outcome Weight control Weight Loss |
| title | A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial |
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