Single-cell transcriptome profiling of sepsis identifies HLA-DRlowS100Ahigh monocytes with immunosuppressive function

Background Sustained yet intractable immunosuppression is commonly observed in septic patients, resulting in aggravated clinical outcomes. However, due to the substantial heterogeneity within septic patients, precise indicators in deciphering clinical trajectories and immunological alterations for s...

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Veröffentlicht in:	Military Medical Research 2023-06, Vol.10 (1), p.1-27, Article 27
Hauptverfasser:	Yao, Ren-Qi, Zhao, Peng-Yue, Li, Zhi-Xuan, Liu, Yu-Yang, Zheng, Li-Yu, Duan, Yu, Wang, Lu, Yang, Rong-Li, Kang, Hong-Jun, Hao, Ji-Wei, Li, Jing-Yan, Dong, Ning, Wu, Yao, Du, Xiao-Hui, Zhu, Feng, Ren, Chao, Wu, Guo-Sheng, Xia, Zhao-Fan, Yao, Yong-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Coronaviruses COVID-19 Datasets Gene expression Histocompatibility antigens HLA histocompatibility antigens Immune response Immunology Immunotherapy Infection Laboratory animals Ligands Mortality RNA sequencing Sepsis T cells
Online-Zugang:	Volltext
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