Corticosteroid-Induced Psychosis: A Report of Three Cases

Corticosteroids are commonly used for pain management and inflammatory conditions but can cause neuropsychiatric complications ranging from anxiety to severe mood and psychotic symptoms. These complications can occur shortly after steroid treatment begins or at any point during therapy, and even aft...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2023-05, Vol.15 (5), p.e39221
Hauptverfasser: Bachu, Anil K, Davis, Victoria, Abdulrahim, Mouad, Harbaugh, Lauren, Prasad, Sakshi, Kotapati, Vijaya Padma, Srinivas, Sushma
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 5
container_start_page e39221
container_title Curēus (Palo Alto, CA)
container_volume 15
creator Bachu, Anil K
Davis, Victoria
Abdulrahim, Mouad
Harbaugh, Lauren
Prasad, Sakshi
Kotapati, Vijaya Padma
Srinivas, Sushma
description Corticosteroids are commonly used for pain management and inflammatory conditions but can cause neuropsychiatric complications ranging from anxiety to severe mood and psychotic symptoms. These complications can occur shortly after steroid treatment begins or at any point during therapy, and even after treatment has stopped. We present three cases of corticosteroid-induced psychosis in patients being treated for pain. The mechanism behind these complications is not fully understood, but stress on the hypothalamic-pituitary-adrenal (HPA) axis is thought to play a role. Clinicians should be cautious and regularly evaluate patients to minimize the risk of complications. More research is needed to understand the underlying pathophysiology.
doi_str_mv 10.7759/cureus.39221
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10276927</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2831727854</sourcerecordid><originalsourceid>FETCH-LOGICAL-c310t-74dbd364758d433040d36919919b38895fea60a108f35ef1d36d57feaaf5b4c63</originalsourceid><addsrcrecordid>eNpVkNtLwzAUxoMobsy9-SwFX-3MrU3qi4ziZTBQZD6HNBfXsTUzaYX990Y7x4QD5_bjO4cPgEsEJ4xlxa3qvOnChBQYoxMwxCjnKUecnh7VAzAOYQUhRJBhyOA5GBBGCKM8H4KidL6tlQut8a7W6azRnTI6eQ07tXShDnfJNHkz20glziaLpTcmKWUw4QKcWbkOZrzPI_D--LAon9P5y9OsnM5TRRBsU0Z1pUlOWcY1JQRSGLsCFTEqwnmRWSNzKBHklmTGorjVGYtDabOKqpyMwH2vu-2qjdHKNK2Xa7H19Ub6nXCyFv83Tb0UH-5LIIhZXmAWFa73Ct59dia0YuU638SnBeYEMcx4RiN101PKuxC8sYcTCIofs0Vvtvg1O-JXx28d4D9ryTdwgHr9</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2831727854</pqid></control><display><type>article</type><title>Corticosteroid-Induced Psychosis: A Report of Three Cases</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Bachu, Anil K ; Davis, Victoria ; Abdulrahim, Mouad ; Harbaugh, Lauren ; Prasad, Sakshi ; Kotapati, Vijaya Padma ; Srinivas, Sushma</creator><creatorcontrib>Bachu, Anil K ; Davis, Victoria ; Abdulrahim, Mouad ; Harbaugh, Lauren ; Prasad, Sakshi ; Kotapati, Vijaya Padma ; Srinivas, Sushma</creatorcontrib><description>Corticosteroids are commonly used for pain management and inflammatory conditions but can cause neuropsychiatric complications ranging from anxiety to severe mood and psychotic symptoms. These complications can occur shortly after steroid treatment begins or at any point during therapy, and even after treatment has stopped. We present three cases of corticosteroid-induced psychosis in patients being treated for pain. The mechanism behind these complications is not fully understood, but stress on the hypothalamic-pituitary-adrenal (HPA) axis is thought to play a role. Clinicians should be cautious and regularly evaluate patients to minimize the risk of complications. More research is needed to understand the underlying pathophysiology.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.39221</identifier><identifier>PMID: 37337486</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Antipsychotics ; Catatonia ; Dementia ; Hospitalization ; Internal Medicine ; Medical Education ; Pain management ; Paranoia ; Patients ; Psychiatry ; Psychosis ; Psychotropic drugs ; Sleep ; Steroids</subject><ispartof>Curēus (Palo Alto, CA), 2023-05, Vol.15 (5), p.e39221</ispartof><rights>Copyright © 2023, Bachu et al.</rights><rights>Copyright © 2023, Bachu et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Bachu et al. 2023 Bachu et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c310t-74dbd364758d433040d36919919b38895fea60a108f35ef1d36d57feaaf5b4c63</citedby><cites>FETCH-LOGICAL-c310t-74dbd364758d433040d36919919b38895fea60a108f35ef1d36d57feaaf5b4c63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276927/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276927/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37337486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bachu, Anil K</creatorcontrib><creatorcontrib>Davis, Victoria</creatorcontrib><creatorcontrib>Abdulrahim, Mouad</creatorcontrib><creatorcontrib>Harbaugh, Lauren</creatorcontrib><creatorcontrib>Prasad, Sakshi</creatorcontrib><creatorcontrib>Kotapati, Vijaya Padma</creatorcontrib><creatorcontrib>Srinivas, Sushma</creatorcontrib><title>Corticosteroid-Induced Psychosis: A Report of Three Cases</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Corticosteroids are commonly used for pain management and inflammatory conditions but can cause neuropsychiatric complications ranging from anxiety to severe mood and psychotic symptoms. These complications can occur shortly after steroid treatment begins or at any point during therapy, and even after treatment has stopped. We present three cases of corticosteroid-induced psychosis in patients being treated for pain. The mechanism behind these complications is not fully understood, but stress on the hypothalamic-pituitary-adrenal (HPA) axis is thought to play a role. Clinicians should be cautious and regularly evaluate patients to minimize the risk of complications. More research is needed to understand the underlying pathophysiology.</description><subject>Antipsychotics</subject><subject>Catatonia</subject><subject>Dementia</subject><subject>Hospitalization</subject><subject>Internal Medicine</subject><subject>Medical Education</subject><subject>Pain management</subject><subject>Paranoia</subject><subject>Patients</subject><subject>Psychiatry</subject><subject>Psychosis</subject><subject>Psychotropic drugs</subject><subject>Sleep</subject><subject>Steroids</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkNtLwzAUxoMobsy9-SwFX-3MrU3qi4ziZTBQZD6HNBfXsTUzaYX990Y7x4QD5_bjO4cPgEsEJ4xlxa3qvOnChBQYoxMwxCjnKUecnh7VAzAOYQUhRJBhyOA5GBBGCKM8H4KidL6tlQut8a7W6azRnTI6eQ07tXShDnfJNHkz20glziaLpTcmKWUw4QKcWbkOZrzPI_D--LAon9P5y9OsnM5TRRBsU0Z1pUlOWcY1JQRSGLsCFTEqwnmRWSNzKBHklmTGorjVGYtDabOKqpyMwH2vu-2qjdHKNK2Xa7H19Ub6nXCyFv83Tb0UH-5LIIhZXmAWFa73Ct59dia0YuU638SnBeYEMcx4RiN101PKuxC8sYcTCIofs0Vvtvg1O-JXx28d4D9ryTdwgHr9</recordid><startdate>20230519</startdate><enddate>20230519</enddate><creator>Bachu, Anil K</creator><creator>Davis, Victoria</creator><creator>Abdulrahim, Mouad</creator><creator>Harbaugh, Lauren</creator><creator>Prasad, Sakshi</creator><creator>Kotapati, Vijaya Padma</creator><creator>Srinivas, Sushma</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20230519</creationdate><title>Corticosteroid-Induced Psychosis: A Report of Three Cases</title><author>Bachu, Anil K ; Davis, Victoria ; Abdulrahim, Mouad ; Harbaugh, Lauren ; Prasad, Sakshi ; Kotapati, Vijaya Padma ; Srinivas, Sushma</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-74dbd364758d433040d36919919b38895fea60a108f35ef1d36d57feaaf5b4c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antipsychotics</topic><topic>Catatonia</topic><topic>Dementia</topic><topic>Hospitalization</topic><topic>Internal Medicine</topic><topic>Medical Education</topic><topic>Pain management</topic><topic>Paranoia</topic><topic>Patients</topic><topic>Psychiatry</topic><topic>Psychosis</topic><topic>Psychotropic drugs</topic><topic>Sleep</topic><topic>Steroids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bachu, Anil K</creatorcontrib><creatorcontrib>Davis, Victoria</creatorcontrib><creatorcontrib>Abdulrahim, Mouad</creatorcontrib><creatorcontrib>Harbaugh, Lauren</creatorcontrib><creatorcontrib>Prasad, Sakshi</creatorcontrib><creatorcontrib>Kotapati, Vijaya Padma</creatorcontrib><creatorcontrib>Srinivas, Sushma</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bachu, Anil K</au><au>Davis, Victoria</au><au>Abdulrahim, Mouad</au><au>Harbaugh, Lauren</au><au>Prasad, Sakshi</au><au>Kotapati, Vijaya Padma</au><au>Srinivas, Sushma</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Corticosteroid-Induced Psychosis: A Report of Three Cases</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-05-19</date><risdate>2023</risdate><volume>15</volume><issue>5</issue><spage>e39221</spage><pages>e39221-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Corticosteroids are commonly used for pain management and inflammatory conditions but can cause neuropsychiatric complications ranging from anxiety to severe mood and psychotic symptoms. These complications can occur shortly after steroid treatment begins or at any point during therapy, and even after treatment has stopped. We present three cases of corticosteroid-induced psychosis in patients being treated for pain. The mechanism behind these complications is not fully understood, but stress on the hypothalamic-pituitary-adrenal (HPA) axis is thought to play a role. Clinicians should be cautious and regularly evaluate patients to minimize the risk of complications. More research is needed to understand the underlying pathophysiology.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>37337486</pmid><doi>10.7759/cureus.39221</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2023-05, Vol.15 (5), p.e39221
issn 2168-8184
2168-8184
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10276927
source PubMed Central Open Access; PubMed Central
subjects Antipsychotics
Catatonia
Dementia
Hospitalization
Internal Medicine
Medical Education
Pain management
Paranoia
Patients
Psychiatry
Psychosis
Psychotropic drugs
Sleep
Steroids
title Corticosteroid-Induced Psychosis: A Report of Three Cases
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A53%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Corticosteroid-Induced%20Psychosis:%20A%20Report%20of%20Three%20Cases&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Bachu,%20Anil%20K&rft.date=2023-05-19&rft.volume=15&rft.issue=5&rft.spage=e39221&rft.pages=e39221-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.39221&rft_dat=%3Cproquest_pubme%3E2831727854%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2831727854&rft_id=info:pmid/37337486&rfr_iscdi=true