Multiscale Modeling of Hepatitis B Virus Capsid Assembly and Its Dimorphism

Hepatitis B virus (HBV) is an endemic, chronic virus that leads to 800000 deaths per year. Central to the HBV lifecycle, the viral core has a protein capsid assembled from many copies of a single protein. The capsid protein adopts different (quasi-equivalent) conformations to form icosahedral capsid...

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Veröffentlicht in:	ACS nano 2022-09, Vol.16 (9), p.13845-13859
Hauptverfasser:	Mohajerani, Farzaneh, Tyukodi, Botond, Schlicksup, Christopher J., Hadden-Perilla, Jodi A., Zlotnick, Adam, Hagan, Michael F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology Capsid - chemistry Capsid Proteins - chemistry Hepatitis B virus - chemistry Sex Characteristics Virus Assembly
Online-Zugang:	Volltext
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