Revealing Individual Neuroanatomical Heterogeneity in Alzheimer Disease Using Neuroanatomical Normative Modeling

Alzheimer disease (AD) is highly heterogeneous, with marked individual differences in clinical presentation and neurobiology. To explore this, we used neuroanatomical normative modeling to index regional patterns of variability in cortical thickness. We aimed to characterize individual differences a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Neurology 2023-06, Vol.100 (24), p.e2442-e2453
Hauptverfasser:	Verdi, Serena, Kia, Seyed Mostafa, Yong, Keir X.X., Tosun, Duygu, Schott, Jonathan M., Marquand, Andre F., Cole, James H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Amyloid beta-Peptides - metabolism Bayes Theorem Brain - metabolism Cognitive Dysfunction - metabolism Humans Magnetic Resonance Imaging Neuroimaging
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!