IMMU-13. PRECLINICAL EFFICACY OF MULTI-ANTIGEN (HER2/EGFR806/B7-H3/IL13RA2) TARGETING QUAD-CAR T CELLS AGAINST DIFFUSE MIDLINE GLIOMA

Abstract BACKGROUND Diffuse midline glioma (DMG), including diffuse intrinsic pontine glioma (DIPG), remains a fatal disease. We have published the preclinical efficacy of HER2, EGFR806, and B7-H3 CAR-T cells and opened 3 trials (BrainChild-01, -02, and -03, respectively) that have delivered >350...

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Veröffentlicht in:Neuro-oncology (Charlottesville, Va.) Va.), 2023-06, Vol.25 (Supplement_1), p.i52-i52
Hauptverfasser: Myers, Carrie, Timpanaro, Andrea, Song, Edward, Meechan, Michael, Chen, Alex, Biery, Matthew, Reid, Aquene, Gwiazda, Kamila, Baldwin, Michael, Gustafson, Joshua, Gardner, Rebecca, Jensen, Michael, Vitanza, Nicholas
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Sprache:eng
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