IMMU-10. PILOCYTIC ASTROCYTOMAS SHOW EVIDENCE OF INTRINSIC IMMUNE SURVEILLANCE AND ACTIVATION WITHIN THE TUMOR MICROENVIRONMENT

Abstract PURPOSE To clarify the immunoreactivity and potential immunotherapeutic targets of pediatric low- and high-grade gliomas (HGG). METHODS Spatial sequential immunofluorescence (seqIFTM) of 24 protein markers, NanoString analysis of 770 immune genes, and scRNA sequencing were used to profile a...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2023-06, Vol.25 (Supplement_1), p.i51-i51
Hauptverfasser:	Najem, Hinda, Tripathi, Shashwat, McCortney, Kathleen, Horak, Victoria Jane, Leonard, Kaethe, Steffens, Alicia, Walshon, Jordain, Horbinski, Craig M, Wadhwani, Nitin R, James, Charles David, Lam, Sandi, Lesniak, Maciej S, Burks, Jared K, Heimberger, Amy B, DeCuypere, Michael G
Format:	Artikel
Sprache:	eng
Schlagworte:	Final Category: Immunology/Immunotherapy - IMMU
Online-Zugang:	Volltext
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