SURG-06. ENHANCED DELIVERY OF ANTI-PD1 FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA USING FOCUSED ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER OPENING

Abstract Diffuse midline glioma with H3K27 mutation is a fatal central nervous system tumor, most commonly arising in the brainstem. Despite a multitude of clinical trials, prognosis remains poor with a median overall survival of 9-12 months. Immune-checkpoint inhibitors (ICIs) have transformed the...

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Veröffentlicht in:Neuro-oncology (Charlottesville, Va.) Va.), 2023-06, Vol.25 (Supplement_1), p.i73-i73
Hauptverfasser: Kokossis, Danae, Wei, Hong-Jian, Gallitto, Matthew, Yoh, Nina, McQuillan, Nicholas, Tazhibi, Masih, Berg, Xander, Zhang, Xu, Szalontay, Luca, Gartrell, Robyn D, Pavisic, Jovana, Zhang, Zhiguo, Molotkov, Andrei, Mintz, Akiva, Konofagou, Elisa E, Wu, Cheng-Chia
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Sprache:eng
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