Intermolecular interactions and water structure in a condensed phase B-DNA crystal

By controlled dehydration, the unit cells of dodecamer DNA-drug crystals have been shrunk from 68,000 (normal state) to 60,000 (partially dehydrated intermediate state) to 51,000 A(3) (fully dehydrated state), beyond which no further solvent loss occurs. The total solvent content in the normal cryst...

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Veröffentlicht in:Nucleic acids research 2000-03, Vol.28 (5), p.1259-1265
Hauptverfasser: Clark, G R, Squire, C J, Baker, L J, Martin, R F, White, J
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Sprache:eng
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