Kinetics of generic tacrolimus in heart transplantation: A cautionary note

Tacrolimus is a core component of immunosuppressive regimens. This study compared active pharmaceutical ingredient (API) and dissolution kinetics of branded tacrolimus and formulations from three generic manufacturers (Mylan, Dr. Reddy's, Intas) including samples from patients who suffered acut...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2021-07, Vol.40 (7), p.569-572
Hauptverfasser:	Il'Giovine, Zachary J., Williams, J. Bradley, Mason, R. Preston, Sherratt, Samuel C.R., Hsich, Eileen M., Lever, Harry, Mehra, Mandeep R., Starling, Randall C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Drugs, Generic - pharmacokinetics Graft Rejection - immunology Graft Rejection - metabolism Graft Rejection - prevention & control Heart Transplantation Humans Immunosuppression Immunosuppressive Agents - pharmacokinetics pharmacology rejection tacrolimus Tacrolimus - pharmacokinetics
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