Treatment Using Both Voclosporin and Belimumab in Four Patients With Lupus Nephritis

Treatment Using Both Voclosporin and Belimumab in Four Patients With Lupus Nephritis

Nearly 50% of patients with systemic lupus erythematosus (SLE) will develop lupus nephritis (LN). Current treatment regimens for LN are suboptimal as the majority of patients fail to achieve complete renal response after several months of treatment and there are high rates of relapse. We report outc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2023-05, Vol.15 (5), p.e38848
Hauptverfasser: Baum, Rebecca, Geetha, Duruvu, Fatola, Ayotola, Timlin, Homa
Format: Artikel
Sprache:eng
Schlagworte:
Alopecia
Arthritis
Baldness
Biopsy
Coronaviruses
COVID-19
Creatinine
Drug dosages
Internal Medicine
Leukopenia
Lupus
Medicine
Monoclonal antibodies
Nephrology
Patients
Rheumatology
Ulcers
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Nearly 50% of patients with systemic lupus erythematosus (SLE) will develop lupus nephritis (LN). Current treatment regimens for LN are suboptimal as the majority of patients fail to achieve complete renal response after several months of treatment and there are high rates of relapse. We report outcomes in four LN patients who were treated with both voclosporin and belimumab. These patients had no serious infections, and we were able to taper glucocorticoids and reduce proteinuria.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.38848