Discovering a uniform functional trade-off of the CBC-type 2,3-oxidosqualene cyclases and deciphering its chemical logic

Many functionally promiscuous plant 2,3-oxidosqualene cyclases (OSCs) have been found, but complete functional reshaping is rarely reported. In this study, we have identified two new plant OSCs: a unique protostadienol synthase ( PDS) and a common cycloartenol synthase ( CAS) from (Sam.) Juzep. Mult...

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Veröffentlicht in:	Science advances 2023-06, Vol.9 (23), p.eadh1418-eadh1418
Hauptverfasser:	Zhang, Fan, Wang, Yunpeng, Yue, Jingyang, Zhang, Rongrong, Hu, Yong-Er, Huang, Ruoshi, Ji, Ai-Jia, Hess, Jr, B Andes, Liu, Zhongqiu, Duan, Lixin, Wu, Ruibo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedicine and Life Sciences Phenylalanine Plant Sciences SciAdv r-articles Squalene - chemistry Threonine
Online-Zugang:	Volltext
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