The Efficiency of p27 Cleavage during In Vitro Respiratory Syncytial Virus (RSV) Infection Is Cell Line and RSV Subtype Dependent

Respiratory syncytial virus (RSV) fusion protein (F) is highly conserved between subtypes A and B (RSV/A and RSV/B). To become fully active, F precursor undergoes enzymatic cleavage to yield F1 and F2 subunits and releases a 27-amino-acid peptide (p27). Virus-cell fusion occurs when RSV F undergoes...

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Veröffentlicht in:	Journal of virology 2023-05, Vol.97 (5), p.e0025423
Hauptverfasser:	Rezende, Wanderson, Ye, Xunyan, Angelo, Laura S, Carisey, Alexandre F, Avadhanula, Vasanthi, Piedra, Pedro A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Neutralizing Antibodies, Viral Cell Line Humans Respiratory Syncytial Virus Infections Respiratory Syncytial Virus Vaccines Respiratory Syncytial Virus, Human Viral Fusion Proteins - metabolism Virology Virus-Cell Interactions
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