Lack of Age-Appropriate Reference Intervals Causing Potentially Missed Alerts in Clinical Reports of Dyslipidemia

Lack of Age-Appropriate Reference Intervals Causing Potentially Missed Alerts in Clinical Reports of Dyslipidemia

This study shows that only 12.5% of laboratory reports (2/16) included age-appropriate pediatric reference ranges for all lipid and lipoproteins. The use of erroneous reference range(s) could lead to missed alerts of dyslipidemia in up to 97.3% (total cholesterol), 93.6% (high-density lipoprotein ch...

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Veröffentlicht in:The Journal of pediatrics 2023-01, Vol.252, p.208-212.e3
Hauptverfasser: Sena, Cecilia, Ohene-Adjei, Michael, Deng, Shuliang, Patibandla, Nandan, May, Benjamin, de Ferranti, Sarah D., Starc, Thomas J., Thaker, Vidhu V.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Child
Cholesterol, HDL
Cholesterol, LDL
Dyslipidemias - diagnosis
Humans
Nutrition Surveys
Triglycerides
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container_end_page 212.e3
container_issue
container_start_page 208
container_title The Journal of pediatrics
container_volume 252
creator Sena, Cecilia
Ohene-Adjei, Michael
Deng, Shuliang
Patibandla, Nandan
May, Benjamin
de Ferranti, Sarah D.
Starc, Thomas J.
Thaker, Vidhu V.
description This study shows that only 12.5% of laboratory reports (2/16) included age-appropriate pediatric reference ranges for all lipid and lipoproteins. The use of erroneous reference range(s) could lead to missed alerts of dyslipidemia in up to 97.3% (total cholesterol), 93.6% (high-density lipoprotein cholesterol), 94.8% (low-density lipoprotein cholesterol), and 87.8% (triglycerides) of youth in the population-based National Health and Nutrition Examination Survey cohort. These findings highlight the potential missed opportunities for reinforcing lifestyle counseling for dyslipidemia in addition to obesity in youth.
doi_str_mv 10.1016/j.jpeds.2022.08.017
format Article
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adolescent
Child
Cholesterol, HDL
Cholesterol, LDL
Dyslipidemias - diagnosis
Humans
Nutrition Surveys
Triglycerides
title Lack of Age-Appropriate Reference Intervals Causing Potentially Missed Alerts in Clinical Reports of Dyslipidemia
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