Fulminant Mycoplasma pneumoniae pneumonia
The frequency of fulminant pneumonia due to Mycoplasma pneumoniae is relatively rare despite the high prevalence of Mycoplasma species infection in the general population. We recently encountered such a case and have reviewed the English-language literature on cases of M pneumoniae pneumonia that ha...
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Veröffentlicht in: | The Western journal of medicine 1995-02, Vol.162 (2), p.133-142 |
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description | The frequency of fulminant pneumonia due to Mycoplasma pneumoniae is relatively rare despite the high prevalence of Mycoplasma species infection in the general population. We recently encountered such a case and have reviewed the English-language literature on cases of M pneumoniae pneumonia that have resulted in respiratory failure or death. Due to host factors or on epidemiologic grounds, fulminant cases seem to be more common in young healthy adults, in males, and possibly in smokers among the 46 patients we found. An enhanced host cellular immune response may be responsible for the development of severe cases. A spectrum of small airways disease is characteristic, including cellular bronchiolitis and bronchiolitis obliterans with and without organizing pneumonia. Based largely on anecdotal experience, corticosteroid use may be salutary in patients with respiratory failure. For reasons that are not well known, the incidence of pulmonary thromboembolism is increased in fatal cases. Images |
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We recently encountered such a case and have reviewed the English-language literature on cases of M pneumoniae pneumonia that have resulted in respiratory failure or death. Due to host factors or on epidemiologic grounds, fulminant cases seem to be more common in young healthy adults, in males, and possibly in smokers among the 46 patients we found. An enhanced host cellular immune response may be responsible for the development of severe cases. A spectrum of small airways disease is characteristic, including cellular bronchiolitis and bronchiolitis obliterans with and without organizing pneumonia. Based largely on anecdotal experience, corticosteroid use may be salutary in patients with respiratory failure. For reasons that are not well known, the incidence of pulmonary thromboembolism is increased in fatal cases. Images</description><identifier>ISSN: 0093-0415</identifier><identifier>EISSN: 1476-2978</identifier><identifier>PMID: 7725685</identifier><identifier>CODEN: WJMDA2</identifier><language>eng</language><publisher>United States: BMJ Publishing Group Ltd</publisher><subject>Adolescent ; Adrenocortical hormones ; Adult ; Causes of ; Child ; Child, Preschool ; Complications and side effects ; Female ; Humans ; Male ; Middle Aged ; Mycoplasma pneumonia ; Mycoplasma pneumoniae ; Pneumonia, Mycoplasma - complications ; Pneumonia, Mycoplasma - mortality ; Pneumonia, Mycoplasma - physiopathology ; Respiratory insufficiency ; Respiratory Insufficiency - etiology ; Respiratory Insufficiency - mortality ; Respiratory Insufficiency - physiopathology ; Thromboembolism</subject><ispartof>The Western journal of medicine, 1995-02, Vol.162 (2), p.133-142</ispartof><rights>COPYRIGHT 1995 BMJ Publishing Group Ltd.</rights><rights>Copyright BMJ Publishing Group LTD Feb 1995</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1022647/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1022647/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7725685$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, E D</creatorcontrib><creatorcontrib>Welsh, C H</creatorcontrib><title>Fulminant Mycoplasma pneumoniae pneumonia</title><title>The Western journal of medicine</title><addtitle>West J Med</addtitle><description>The frequency of fulminant pneumonia due to Mycoplasma pneumoniae is relatively rare despite the high prevalence of Mycoplasma species infection in the general population. We recently encountered such a case and have reviewed the English-language literature on cases of M pneumoniae pneumonia that have resulted in respiratory failure or death. Due to host factors or on epidemiologic grounds, fulminant cases seem to be more common in young healthy adults, in males, and possibly in smokers among the 46 patients we found. An enhanced host cellular immune response may be responsible for the development of severe cases. A spectrum of small airways disease is characteristic, including cellular bronchiolitis and bronchiolitis obliterans with and without organizing pneumonia. Based largely on anecdotal experience, corticosteroid use may be salutary in patients with respiratory failure. For reasons that are not well known, the incidence of pulmonary thromboembolism is increased in fatal cases. Images</description><subject>Adolescent</subject><subject>Adrenocortical hormones</subject><subject>Adult</subject><subject>Causes of</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Complications and side effects</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mycoplasma pneumonia</subject><subject>Mycoplasma pneumoniae</subject><subject>Pneumonia, Mycoplasma - complications</subject><subject>Pneumonia, Mycoplasma - mortality</subject><subject>Pneumonia, Mycoplasma - physiopathology</subject><subject>Respiratory insufficiency</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Respiratory Insufficiency - mortality</subject><subject>Respiratory Insufficiency - physiopathology</subject><subject>Thromboembolism</subject><issn>0093-0415</issn><issn>1476-2978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkctKAzEUhgdRaq0-glAUBMGBZHJrNkIpjrVUXXhZuAnp9ExNnUnqXMS-vSktbZWCZJGQ8_GdnD97QRNTwcNIis5-0ERIkhBRzA6Do7KcIoQow7IRNISIGO-wZnAZ11lurLZV-36euFmmy1y3Zxbq3FmjYXM8Dg5SnZVwstpbwUt889zrh8PH27tedxhOKEdVmFKJZYo0RgzDWKSIaBFRoCyNIi5lwqUYIappB2hKaCdJmKCERxxAQCSRIK3geumd1aMcxgnYqtCZmhUm18VcOW3U74o172rivhRGvgNdCC5WgsJ91lBWKjdlAlmmLbi6VH52Qjj-H8SMI8Y48eD5H3Dq6sL6FBQWgi10lHnqbElNdAbK2NT55yULpepizrnXLaCrHdAELPhRnIXU-OttPNyB-zWG3CS7-NPt8Naprf574zNlBd_rsi4-FBdEMPXw2lP94dsgHuBYPZEfFg6zxQ</recordid><startdate>19950201</startdate><enddate>19950201</enddate><creator>Chan, E D</creator><creator>Welsh, C H</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19950201</creationdate><title>Fulminant Mycoplasma pneumoniae pneumonia</title><author>Chan, E D ; Welsh, C H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g460t-f4919f0a1051ed7f03a724e45f22699c697b04a48e4f348cc5743626ee7e29073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Adolescent</topic><topic>Adrenocortical hormones</topic><topic>Adult</topic><topic>Causes of</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Complications and side effects</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mycoplasma pneumonia</topic><topic>Mycoplasma pneumoniae</topic><topic>Pneumonia, Mycoplasma - complications</topic><topic>Pneumonia, Mycoplasma - mortality</topic><topic>Pneumonia, Mycoplasma - physiopathology</topic><topic>Respiratory insufficiency</topic><topic>Respiratory Insufficiency - etiology</topic><topic>Respiratory Insufficiency - mortality</topic><topic>Respiratory Insufficiency - physiopathology</topic><topic>Thromboembolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, E D</creatorcontrib><creatorcontrib>Welsh, C H</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Western journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, E D</au><au>Welsh, C H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fulminant Mycoplasma pneumoniae pneumonia</atitle><jtitle>The Western journal of medicine</jtitle><addtitle>West J Med</addtitle><date>1995-02-01</date><risdate>1995</risdate><volume>162</volume><issue>2</issue><spage>133</spage><epage>142</epage><pages>133-142</pages><issn>0093-0415</issn><eissn>1476-2978</eissn><coden>WJMDA2</coden><abstract>The frequency of fulminant pneumonia due to Mycoplasma pneumoniae is relatively rare despite the high prevalence of Mycoplasma species infection in the general population. We recently encountered such a case and have reviewed the English-language literature on cases of M pneumoniae pneumonia that have resulted in respiratory failure or death. Due to host factors or on epidemiologic grounds, fulminant cases seem to be more common in young healthy adults, in males, and possibly in smokers among the 46 patients we found. An enhanced host cellular immune response may be responsible for the development of severe cases. A spectrum of small airways disease is characteristic, including cellular bronchiolitis and bronchiolitis obliterans with and without organizing pneumonia. Based largely on anecdotal experience, corticosteroid use may be salutary in patients with respiratory failure. For reasons that are not well known, the incidence of pulmonary thromboembolism is increased in fatal cases. Images</abstract><cop>United States</cop><pub>BMJ Publishing Group Ltd</pub><pmid>7725685</pmid><tpages>10</tpages></addata></record> |
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subjects | Adolescent Adrenocortical hormones Adult Causes of Child Child, Preschool Complications and side effects Female Humans Male Middle Aged Mycoplasma pneumonia Mycoplasma pneumoniae Pneumonia, Mycoplasma - complications Pneumonia, Mycoplasma - mortality Pneumonia, Mycoplasma - physiopathology Respiratory insufficiency Respiratory Insufficiency - etiology Respiratory Insufficiency - mortality Respiratory Insufficiency - physiopathology Thromboembolism |
title | Fulminant Mycoplasma pneumoniae pneumonia |
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