Primary extrahepatic biliary neuroendocrine tumor: a case report
Abstract Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Com...
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Veröffentlicht in: | Journal of surgical case reports 2023-05, Vol.2023 (5), p.rjad277 |
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creator | Taj, Raeda Perez, Sean Jih, Lily J Huynh, Christina Berumen, Jennifer Bouvet, Michael |
description | Abstract
Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection. |
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Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection.</description><identifier>ISSN: 2042-8812</identifier><identifier>EISSN: 2042-8812</identifier><identifier>DOI: 10.1093/jscr/rjad277</identifier><identifier>PMID: 37251245</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Case Report</subject><ispartof>Journal of surgical case reports, 2023-05, Vol.2023 (5), p.rjad277</ispartof><rights>Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. 2023</rights><rights>Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c341t-76c5fbe9faa25fb3db6edf20a712272d55eae00f8ac9f076a4e12e2cc88b89363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224785/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224785/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,883,1601,27911,27912,53778,53780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37251245$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taj, Raeda</creatorcontrib><creatorcontrib>Perez, Sean</creatorcontrib><creatorcontrib>Jih, Lily J</creatorcontrib><creatorcontrib>Huynh, Christina</creatorcontrib><creatorcontrib>Berumen, Jennifer</creatorcontrib><creatorcontrib>Bouvet, Michael</creatorcontrib><title>Primary extrahepatic biliary neuroendocrine tumor: a case report</title><title>Journal of surgical case reports</title><addtitle>J Surg Case Rep</addtitle><description>Abstract
Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection.</description><subject>Case Report</subject><issn>2042-8812</issn><issn>2042-8812</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><recordid>eNp9UD1PwzAQtRCIVqUbM8rGQqh9-bDDAqjiS6oEA8yW45ypqzaO7ATBvydVCioLt9zT3bt3T4-QU0YvGS2S2SpoP_MrVQHnB2QMNIVYCAaHe3hEpiGsaF9pwZjIj8ko4ZAxSLMxuXnxdqP8V4SfrVdLbFRrdVTatd0Oa-y8w7py2tsao7bbOH8VqUirgJHHxvn2hBwZtQ443fUJebu_e50_xovnh6f57SLWScramOc6MyUWRinoQVKVOVYGqOIMgEOVZaiQUiOULgzluUqRAYLWQpSiSPJkQq4H3aYrN1hprHu_a9kM9qVTVv7d1HYp392HZBQg5SLrFS4GBe1dCB7N7zGjcpum3KYpd2n29LP9h7_kn-x6wvlAcF3zv9Q3cWmB_w</recordid><startdate>20230501</startdate><enddate>20230501</enddate><creator>Taj, Raeda</creator><creator>Perez, Sean</creator><creator>Jih, Lily J</creator><creator>Huynh, Christina</creator><creator>Berumen, Jennifer</creator><creator>Bouvet, Michael</creator><general>Oxford University Press</general><scope>TOX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20230501</creationdate><title>Primary extrahepatic biliary neuroendocrine tumor: a case report</title><author>Taj, Raeda ; Perez, Sean ; Jih, Lily J ; Huynh, Christina ; Berumen, Jennifer ; Bouvet, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-76c5fbe9faa25fb3db6edf20a712272d55eae00f8ac9f076a4e12e2cc88b89363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Case Report</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taj, Raeda</creatorcontrib><creatorcontrib>Perez, Sean</creatorcontrib><creatorcontrib>Jih, Lily J</creatorcontrib><creatorcontrib>Huynh, Christina</creatorcontrib><creatorcontrib>Berumen, Jennifer</creatorcontrib><creatorcontrib>Bouvet, Michael</creatorcontrib><collection>Oxford Journals Open Access Collection</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of surgical case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taj, Raeda</au><au>Perez, Sean</au><au>Jih, Lily J</au><au>Huynh, Christina</au><au>Berumen, Jennifer</au><au>Bouvet, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary extrahepatic biliary neuroendocrine tumor: a case report</atitle><jtitle>Journal of surgical case reports</jtitle><addtitle>J Surg Case Rep</addtitle><date>2023-05-01</date><risdate>2023</risdate><volume>2023</volume><issue>5</issue><spage>rjad277</spage><pages>rjad277-</pages><issn>2042-8812</issn><eissn>2042-8812</eissn><abstract>Abstract
Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>37251245</pmid><doi>10.1093/jscr/rjad277</doi><oa>free_for_read</oa></addata></record> |
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title | Primary extrahepatic biliary neuroendocrine tumor: a case report |
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