Performance Enhancement of PLA-Based Blend Microneedle Arrays through Shish-Kebab Structuring Strategy in Microinjection Molding

Poly(lactic acid) (PLA) microneedles have been explored extensively, but the current regular fabrication strategy, such as thermoforming, is inefficient and poorly conformable. In addition, PLA needs to be modified as the application of microneedle arrays made of pure PLA is limited because of their...

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Veröffentlicht in:	Polymers 2023-05, Vol.15 (10), p.2234
Hauptverfasser:	Zhang, Lifan, Chen, Yinghong, Tan, Jiayu, Feng, Shuo, Xie, Yeping, Li, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Arrays Biocompatibility Biodegradable materials Crystallization Dispersion Efficiency Elongation Fractures Identification and classification Industrial applications Injection molding Lactic acid Lactones Manufacturing Mechanical properties Medical equipment Methods Microneedle drug delivery Modulus of elasticity Needles Polylactic acid Polymers Properties Shear stress Stiffness Stress distribution Structure Tensile strength Tensile tests Thermoforming Transdermal medication
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