Complex Formation of an RNA Aptamer with a Part of HIV-1 Tat through Induction of Base Triples in Living Human Cells Proven by In-Cell NMR

An RNA aptamer that strongly binds to a target molecule has the potential to be a nucleic acid drug inside living human cells. To investigate and improve this potential, it is critical to elucidate the structure and interaction of RNA aptamers inside living cells. We examined an RNA aptamer for HIV-...

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Veröffentlicht in:International journal of molecular sciences 2023-05, Vol.24 (10), p.9069
Hauptverfasser: Eladl, Omar, Yamaoki, Yudai, Kondo, Keiko, Nagata, Takashi, Katahira, Masato
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Sprache:eng
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