Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway

Abnormal fibroblast proliferation and excessive extracellular matrix (ECM) deposition lead to the formation of hypertrophic scars (HSs). However, there is no satisfactory method to inhibit the occurrence and development of HSs. In our study, platycodin D (PD), a natural compound extracted from Platy...

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Veröffentlicht in:Archives of Dermatological Research 2023-07, Vol.315 (5), p.1257-1267
Hauptverfasser: Yu, Zhencheng, Li, Yun, Fu, Rao, Xue, Yaxin, Zhao, Danyang, Han, Dong
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Sprache:eng
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