Haldol Targets IQGAP1 Pathway and Promotes Novel Partner Interactions in Glioblastoma Cell Lines

Glioblastoma multiform (GBM) is an incurable heterogenous brain cancer with few clinical target options. IQGAP1 is a scaffold oncoprotein involved in GBM with unclear mechanism. Here we report that the antipsychotic drug Haldol differentially alters IQGAP1 signaling and inhibits GBM cell proliferati...

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Veröffentlicht in:	microPublication biology 2023, Vol.2023
Hauptverfasser:	Iyer, Varun J., Osman, Mahasin A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Human Models of Human Disease New Finding
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