Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family

HIV-1-associated blood brain barrier (BBB) alterations and neurocognitive disorders are frequent clinical manifestations in HIV-1 infected patients. The BBB is formed by cells of the neurovascular unit (NVU) and sealed together by tight junction proteins, such as occludin (ocln). Pericytes are a key...

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Veröffentlicht in:	Molecular neurobiology 2023-09, Vol.60 (9), p.4966-4982
Hauptverfasser:	Torices, Silvia, Teglas, Timea, Naranjo, Oandy, Fattakhov, Nikolai, Frydlova, Kristyna, Cabrera, Rosalba, Osborne, Olivia M., Sun, Enze, Kluttz, Allan, Toborek, Michal
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Blood-brain barrier Brain Cell Biology Cognition HIV Human immunodeficiency virus Immune system Infections Interferon Molecular modelling mRNA Neurobiology Neurology Neurosciences Pericytes Signal transduction Viral infections
Online-Zugang:	Volltext
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