Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight

Ethyl chloride is a common topical anesthetic. However, when abused as an inhalant, effects can range from headaches and dizziness to debilitating neurotoxicity requiring intubation. While previous case reports describe the short-term reversible neurotoxicity of ethyl chloride, ours show chronic mor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2023-04, Vol.15 (4), p.e37795
Hauptverfasser: Young, 4th, Robert, Carter, Cody, Cardinali, Serge, Khan, Zeryab, Bennett, Katelyn, Jarosz, Amy, Sobecki, Jeffery, Sharma, Rupali, Martin, Ryan
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 4
container_start_page e37795
container_title Curēus (Palo Alto, CA)
container_volume 15
creator Young, 4th, Robert
Carter, Cody
Cardinali, Serge
Khan, Zeryab
Bennett, Katelyn
Jarosz, Amy
Sobecki, Jeffery
Sharma, Rupali
Martin, Ryan
description Ethyl chloride is a common topical anesthetic. However, when abused as an inhalant, effects can range from headaches and dizziness to debilitating neurotoxicity requiring intubation. While previous case reports describe the short-term reversible neurotoxicity of ethyl chloride, ours show chronic morbidity and mortality outcome. During the initial evaluation, it is essential to consider the rising trend of commercially available inhalants being used as recreational drugs. We present a case of a middle-aged man presenting with subacute neurotoxicity due to repeated abuse of ethyl chloride.
doi_str_mv 10.7759/cureus.37795
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10195209</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2821271561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c310t-d9a919999889b15493d3ec0a4fb8e0eb28607f1c6403807bbdb9da2e0637ca033</originalsourceid><addsrcrecordid>eNpVkd9LwzAQx4MobqhvPkvBV6eXpG0SX2QMdQOZ4o_nkKZpm9ElM23F-ddbncq8h7uD-_C9474IHWM4ZywRF7oLpmvOKWMi2UFDglM-4pjHu1v9AB01zQIAMDACDPbRgDKCY0jJEM0fjfalsx_WldF1W63raFLVPtjcRHPTBd_6d6ttu76MZq5StXJtNM66xkRTm-fGRdZFD7Xq85Mtq_YQ7RWqbszRTz1ALzfXz5Pp6O7-djYZ3400xdCOcqEEFn1wLjKcxILm1GhQcZFxAyYjPAVWYJ3GQDmwLMszkStiIKVMK6D0AF1tdFddtjS5Nq4NqparYJcqrKVXVv6fOFvJ0r9JDFgkBESvcPqjEPxrZ5pWLnwXXH-0JJxgwnCS4p4621A6-KYJpvhbgUF-OSA3DshvB3r8ZPusP_j33_QT1IaC-Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2821271561</pqid></control><display><type>article</type><title>Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Young, 4th, Robert ; Carter, Cody ; Cardinali, Serge ; Khan, Zeryab ; Bennett, Katelyn ; Jarosz, Amy ; Sobecki, Jeffery ; Sharma, Rupali ; Martin, Ryan</creator><creatorcontrib>Young, 4th, Robert ; Carter, Cody ; Cardinali, Serge ; Khan, Zeryab ; Bennett, Katelyn ; Jarosz, Amy ; Sobecki, Jeffery ; Sharma, Rupali ; Martin, Ryan</creatorcontrib><description>Ethyl chloride is a common topical anesthetic. However, when abused as an inhalant, effects can range from headaches and dizziness to debilitating neurotoxicity requiring intubation. While previous case reports describe the short-term reversible neurotoxicity of ethyl chloride, ours show chronic morbidity and mortality outcome. During the initial evaluation, it is essential to consider the rising trend of commercially available inhalants being used as recreational drugs. We present a case of a middle-aged man presenting with subacute neurotoxicity due to repeated abuse of ethyl chloride.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.37795</identifier><identifier>PMID: 37214062</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Ataxia ; Cardiac arrhythmia ; Case reports ; Chloride ; Cognitive ability ; Drug dosages ; Hallucinations ; Headaches ; Hydrocarbons ; Mental depression ; Mortality ; Nausea ; Neurology ; Ophthalmology ; Patients ; Physical therapy ; Recreational drugs ; Solvent abuse ; Substance Use and Addiction</subject><ispartof>Curēus (Palo Alto, CA), 2023-04, Vol.15 (4), p.e37795</ispartof><rights>Copyright © 2023, Young et al.</rights><rights>Copyright © 2023, Young et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Young et al. 2023 Young et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c310t-d9a919999889b15493d3ec0a4fb8e0eb28607f1c6403807bbdb9da2e0637ca033</citedby><cites>FETCH-LOGICAL-c310t-d9a919999889b15493d3ec0a4fb8e0eb28607f1c6403807bbdb9da2e0637ca033</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195209/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195209/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37214062$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Young, 4th, Robert</creatorcontrib><creatorcontrib>Carter, Cody</creatorcontrib><creatorcontrib>Cardinali, Serge</creatorcontrib><creatorcontrib>Khan, Zeryab</creatorcontrib><creatorcontrib>Bennett, Katelyn</creatorcontrib><creatorcontrib>Jarosz, Amy</creatorcontrib><creatorcontrib>Sobecki, Jeffery</creatorcontrib><creatorcontrib>Sharma, Rupali</creatorcontrib><creatorcontrib>Martin, Ryan</creatorcontrib><title>Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Ethyl chloride is a common topical anesthetic. However, when abused as an inhalant, effects can range from headaches and dizziness to debilitating neurotoxicity requiring intubation. While previous case reports describe the short-term reversible neurotoxicity of ethyl chloride, ours show chronic morbidity and mortality outcome. During the initial evaluation, it is essential to consider the rising trend of commercially available inhalants being used as recreational drugs. We present a case of a middle-aged man presenting with subacute neurotoxicity due to repeated abuse of ethyl chloride.</description><subject>Ataxia</subject><subject>Cardiac arrhythmia</subject><subject>Case reports</subject><subject>Chloride</subject><subject>Cognitive ability</subject><subject>Drug dosages</subject><subject>Hallucinations</subject><subject>Headaches</subject><subject>Hydrocarbons</subject><subject>Mental depression</subject><subject>Mortality</subject><subject>Nausea</subject><subject>Neurology</subject><subject>Ophthalmology</subject><subject>Patients</subject><subject>Physical therapy</subject><subject>Recreational drugs</subject><subject>Solvent abuse</subject><subject>Substance Use and Addiction</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkd9LwzAQx4MobqhvPkvBV6eXpG0SX2QMdQOZ4o_nkKZpm9ElM23F-ddbncq8h7uD-_C9474IHWM4ZywRF7oLpmvOKWMi2UFDglM-4pjHu1v9AB01zQIAMDACDPbRgDKCY0jJEM0fjfalsx_WldF1W63raFLVPtjcRHPTBd_6d6ttu76MZq5StXJtNM66xkRTm-fGRdZFD7Xq85Mtq_YQ7RWqbszRTz1ALzfXz5Pp6O7-djYZ3400xdCOcqEEFn1wLjKcxILm1GhQcZFxAyYjPAVWYJ3GQDmwLMszkStiIKVMK6D0AF1tdFddtjS5Nq4NqparYJcqrKVXVv6fOFvJ0r9JDFgkBESvcPqjEPxrZ5pWLnwXXH-0JJxgwnCS4p4621A6-KYJpvhbgUF-OSA3DshvB3r8ZPusP_j33_QT1IaC-Q</recordid><startdate>20230418</startdate><enddate>20230418</enddate><creator>Young, 4th, Robert</creator><creator>Carter, Cody</creator><creator>Cardinali, Serge</creator><creator>Khan, Zeryab</creator><creator>Bennett, Katelyn</creator><creator>Jarosz, Amy</creator><creator>Sobecki, Jeffery</creator><creator>Sharma, Rupali</creator><creator>Martin, Ryan</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20230418</creationdate><title>Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight</title><author>Young, 4th, Robert ; Carter, Cody ; Cardinali, Serge ; Khan, Zeryab ; Bennett, Katelyn ; Jarosz, Amy ; Sobecki, Jeffery ; Sharma, Rupali ; Martin, Ryan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c310t-d9a919999889b15493d3ec0a4fb8e0eb28607f1c6403807bbdb9da2e0637ca033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Ataxia</topic><topic>Cardiac arrhythmia</topic><topic>Case reports</topic><topic>Chloride</topic><topic>Cognitive ability</topic><topic>Drug dosages</topic><topic>Hallucinations</topic><topic>Headaches</topic><topic>Hydrocarbons</topic><topic>Mental depression</topic><topic>Mortality</topic><topic>Nausea</topic><topic>Neurology</topic><topic>Ophthalmology</topic><topic>Patients</topic><topic>Physical therapy</topic><topic>Recreational drugs</topic><topic>Solvent abuse</topic><topic>Substance Use and Addiction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Young, 4th, Robert</creatorcontrib><creatorcontrib>Carter, Cody</creatorcontrib><creatorcontrib>Cardinali, Serge</creatorcontrib><creatorcontrib>Khan, Zeryab</creatorcontrib><creatorcontrib>Bennett, Katelyn</creatorcontrib><creatorcontrib>Jarosz, Amy</creatorcontrib><creatorcontrib>Sobecki, Jeffery</creatorcontrib><creatorcontrib>Sharma, Rupali</creatorcontrib><creatorcontrib>Martin, Ryan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Young, 4th, Robert</au><au>Carter, Cody</au><au>Cardinali, Serge</au><au>Khan, Zeryab</au><au>Bennett, Katelyn</au><au>Jarosz, Amy</au><au>Sobecki, Jeffery</au><au>Sharma, Rupali</au><au>Martin, Ryan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-04-18</date><risdate>2023</risdate><volume>15</volume><issue>4</issue><spage>e37795</spage><pages>e37795-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Ethyl chloride is a common topical anesthetic. However, when abused as an inhalant, effects can range from headaches and dizziness to debilitating neurotoxicity requiring intubation. While previous case reports describe the short-term reversible neurotoxicity of ethyl chloride, ours show chronic morbidity and mortality outcome. During the initial evaluation, it is essential to consider the rising trend of commercially available inhalants being used as recreational drugs. We present a case of a middle-aged man presenting with subacute neurotoxicity due to repeated abuse of ethyl chloride.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>37214062</pmid><doi>10.7759/cureus.37795</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2023-04, Vol.15 (4), p.e37795
issn 2168-8184
2168-8184
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10195209
source PubMed Central Open Access; PubMed Central
subjects Ataxia
Cardiac arrhythmia
Case reports
Chloride
Cognitive ability
Drug dosages
Hallucinations
Headaches
Hydrocarbons
Mental depression
Mortality
Nausea
Neurology
Ophthalmology
Patients
Physical therapy
Recreational drugs
Solvent abuse
Substance Use and Addiction
title Recognizing Ethyl Chloride Neurotoxicity: Inhalant Abuse Hidden in Plain Sight
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T02%3A49%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recognizing%20Ethyl%20Chloride%20Neurotoxicity:%20Inhalant%20Abuse%20Hidden%20in%20Plain%20Sight&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Young,%204th,%20Robert&rft.date=2023-04-18&rft.volume=15&rft.issue=4&rft.spage=e37795&rft.pages=e37795-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.37795&rft_dat=%3Cproquest_pubme%3E2821271561%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2821271561&rft_id=info:pmid/37214062&rfr_iscdi=true