Polymer folding through active processes recreates features of genome organization

From proteins to chromosomes, polymers fold into specific conformations that control their biological function. Polymer folding has long been studied with equilibrium thermodynamics, yet intracellular organization and regulation involve energy-consuming, active processes. Signatures of activity have...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2023-05, Vol.120 (20), p.e2221726120
Hauptverfasser: Goychuk, Andriy, Kannan, Deepti, Chakraborty, Arup K, Kardar, Mehran
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Sprache:eng
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