Structural modification of the Pseudomonas aeruginosa alkylquinoline cell-cell communication signal, HHQ, leads to benzofuranoquinolines with anti-virulence behaviour in ESKAPE pathogens

Microbial populations have evolved intricate networks of negotiation and communication through which they can coexist in natural and host ecosystems. The nature of these systems can be complex and they are, for the most part, poorly understood at the polymicrobial level. The Pseudomonas Quinolone Si...

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Veröffentlicht in:Microbiology (Society for General Microbiology) 2023-03, Vol.169 (3)
Hauptverfasser: Rossetto, Veronica, Moore-Machacek, Ay'sha, Woods, David F, Galvão, Helena M, Shanahan, Rachel M, Hickey, Aobha, O'Leary, Niall, O'Gara, Fergal, McGlacken, Gerard P, Reen, F Jerry
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Sprache:eng
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