Population Pharmacokinetics and Dosing Optimization of Ceftazidime in Term Asphyxiated Neonates during Controlled Therapeutic Hypothermia

Ceftazidime is an antibiotic commonly used to treat bacterial infections in term neonates undergoing controlled therapeutic hypothermia (TH) for hypoxic-ischemic encephalopathy after perinatal asphyxia. We aimed to describe the population pharmacokinetics (PK) of ceftazidime in asphyxiated neonates...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2023-05, Vol.67 (5), p.e0170722-e0170722
Hauptverfasser:	van der Veer, Marlotte A A, de Haan, Timo R, Franken, Linda G W, Hodiamont, Caspar J, Groenendaal, Floris, Dijk, Peter H, de Boode, Willem P, Simons, Sinno, Dijkman, Koen P, van Straaten, Henrica L M, Rijken, Monique, Cools, Filip, Nuytemans, Debbie H G M, van Kaam, Anton H, Bijleveld, Yuma A, Mathôt, Ron A A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Ceftazidime - pharmacology Humans Hypothermia - drug therapy Hypothermia, Induced Hypoxia-Ischemia, Brain Infant, Newborn Pharmacology
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