Nobiletin Mitigates D-Galactose-Induced Memory Impairment via Improving Hippocampal Neurogenesis in Mice

Memory impairment is a characteristic of brain aging, and it is associated with a decrease in neurogenesis. Therefore, enhancing neurogenesis is a potential method for mitigating brain aging. Nobiletin (NOB) is a natural polymethoxylated flavonoid derived from citrus peels. It acts as an antioxidant...

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Veröffentlicht in:	Nutrients 2023-05, Vol.15 (9), p.2228
Hauptverfasser:	Xiong, Wei, Li, Rongzi, Li, Boying, Wang, Xifan, Wang, Huihui, Sun, Yanan, Wang, Xiaoyu, Li, Yixuan, Ren, Fazheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging (artificial) Aging (natural) Animal cognition Antibodies Bioflavonoids Brain D-Galactose Flavones Flavonoids Galactose Hippocampus Impairment Inflammation Interleukin 1 Interleukin 6 Memory Microglia Neural stem cells Neurogenesis Neurons Neuroprotection Older people Oxidative stress Pp65 protein Stem cells
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