SerpinA3K Deficiency Reduces Oxidative Stress in Acute Kidney Injury

We previously showed that SerpinA3K is present in urine from rats and humans with acute kidney injury (AKI) and chronic kidney disease (CKD). However, the specific role of SerpinA3K during renal pathophysiology is unknown. To begin to understand the role of SerpinA3K on AKI, SerpinA3K-deficient (KOS...

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Veröffentlicht in:	International journal of molecular sciences 2023-04, Vol.24 (9), p.7815
Hauptverfasser:	González-Soria, Isaac, Soto-Valadez, Axel D, Martínez-Rojas, Miguel Angel, Ortega-Trejo, Juan Antonio, Pérez-Villalva, Rosalba, Gamba, Gerardo, Sánchez-Navarro, Andrea, Bobadilla, Norma A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - metabolism Animals Apoptosis BAX protein Biomarkers Creatinine Cytokines FOXO3 protein Gene expression Genotypes Hypoxia Injury prevention Ischemia Kidney - metabolism Kidney diseases Kidneys Mice Morphology Mortality mRNA Oxidants Oxidative Stress Oxidizing agents Proteins Renal function Renal Insufficiency, Chronic - metabolism Reperfusion Reperfusion Injury - metabolism Severe acute respiratory syndrome coronavirus 2 Vascular endothelial growth factor
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