Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer

Mitochondria are regulators of key cellular processes, including energy production and redox homeostasis. Mitochondrial dysfunction is associated with various human diseases, including cancer. Importantly, both structural and functional changes can alter mitochondrial function. Morphologic and quant...

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Veröffentlicht in:	Cancers 2023-04, Vol.15 (9), p.2564
Hauptverfasser:	Rickard, Brittany P, Overchuk, Marta, Chappell, Vesna A, Kemal Ruhi, Mustafa, Sinawang, Prima Dewi, Nguyen Hoang, Tina Thuy, Akin, Demir, Demirci, Utkan, Franco, Walfre, Fenton, Suzanne E, Santos, Janine H, Rizvi, Imran
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Bioenergetics Cancer Cancer therapies Cristae Cytology Development and progression Health aspects Homeostasis Localization Malignancy Membrane potential Metabolism Metabolites Metastases Metastasis Microscopy Mitochondria Mitochondrial DNA Morphology Oxidative stress Proteins Reactive oxygen species Respiration Review Structure-function relationships Therapeutic targets Visualization
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