Autophagic-Related Proteins in Brain Gliomas: Role, Mechanisms, and Targeting Agents

The present review focuses on the phenomenon of autophagy, a catabolic cellular process, which allows for the recycling of damaged organelles, macromolecules, and misfolded proteins. The different steps able to activate autophagy start with the formation of the autophagosome, mainly controlled by th...

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Veröffentlicht in:	Cancers 2023-05, Vol.15 (9), p.2622
Hauptverfasser:	Pizzimenti, Cristina, Fiorentino, Vincenzo, Franchina, Mariausilia, Martini, Maurizio, Giuffrè, Giuseppe, Lentini, Maria, Silvestris, Nicola, Di Pietro, Martina, Fadda, Guido, Tuccari, Giovanni, Ieni, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Autophagy Brain Brain cancer Brain tumors Cell growth Cytoplasm Glioma cells Gliomas Homeostasis Hypoxia Immunosuppressive agents Kinases Macromolecules Metabolism Microenvironments Molecular modelling Organelles Patients Phosphorylation Physiology Protein folding Proteins Review Stem cells Transcription factors Tumor suppressor genes Tumors
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